Controlled-Release Delivery System for the α-MSH Analog Melanotan-I Using Poloxamer 407

The overall objective of these studies was to develop a controlled-release formulation of Melanotan-I (MT-I) containing poloxamer 407 (P407). Various aqueous formulations were evaluated containing MT-I and 25% w/v P407 alone, or with one of the following additives present, i.e., poly(vinylpyrrolidon...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1996-09, Vol.85 (9), p.915-919
Hauptverfasser:	Bhardwaj, Renu, Blanchard, James
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-MSH - administration & dosage alpha-MSH - analogs & derivatives alpha-MSH - chemistry alpha-MSH - pharmacokinetics Animals Anticarcinogenic Agents - administration & dosage Biological and medical sciences Drug Delivery Systems Guinea Pigs Hormones. Endocrine system Medical sciences Pharmacology. Drug treatments Poloxalene - administration & dosage Solubility Temperature Viscosity
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