Antibiotic prophylaxis and tourniquet application in podiatric surgery
The use of prophylactic antibiosis in podiatric surgery is common, especially in patients undergoing endoprosthetic procedures, major arthrodeses, lengthy procedures, or in immunocompromised patients. The goal of prophylaxis is to prevent infection. For this to occur, there must be an adequate conce...
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| Veröffentlicht in: | The Journal of foot and ankle surgery 1996-07, Vol.35 (4), p.344-349 |
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| container_end_page | 349 |
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| container_issue | 4 |
| container_start_page | 344 |
| container_title | The Journal of foot and ankle surgery |
| container_volume | 35 |
| creator | Deacon, Jeffery S. Wertheimer, Stuart J. Washington, John A. |
| description | The use of prophylactic antibiosis in podiatric surgery is common, especially in patients undergoing endoprosthetic procedures, major arthrodeses, lengthy procedures, or in immunocompromised patients. The goal of prophylaxis is to prevent infection. For this to occur, there must be an adequate concentration of the antimicrobial agent in the tissue at the time of the incision. Historically, prophylaxis has consisted of intravenous administration of 1 gm. of cefazolin, 30 to 60 minutes prior to surgery. Cefazolin concentrations in the medial eminence of the first metatarsal were measured in patients undergoing bunionectomy procedures where pneumatic ankle tourniquets were used for hemostasis. The goal of this study was to determine if the current standards of prophylactic antibiotic administration provide adequate bone levels of cefazolin to effectively inhibit potential infection-causing pathogens. |
| doi_str_mv | 10.1016/S1067-2516(96)80085-8 |
| format | Article |
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The goal of prophylaxis is to prevent infection. For this to occur, there must be an adequate concentration of the antimicrobial agent in the tissue at the time of the incision. Historically, prophylaxis has consisted of intravenous administration of 1 gm. of cefazolin, 30 to 60 minutes prior to surgery. Cefazolin concentrations in the medial eminence of the first metatarsal were measured in patients undergoing bunionectomy procedures where pneumatic ankle tourniquets were used for hemostasis. The goal of this study was to determine if the current standards of prophylactic antibiotic administration provide adequate bone levels of cefazolin to effectively inhibit potential infection-causing pathogens.</description><identifier>ISSN: 1067-2516</identifier><identifier>EISSN: 1542-2224</identifier><identifier>DOI: 10.1016/S1067-2516(96)80085-8</identifier><identifier>PMID: 8872759</identifier><language>eng</language><publisher>Baltimore, MD: Elsevier Inc</publisher><subject>Adult ; Antibacterial agents ; Antibiotic Prophylaxis ; antibiotics ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Cefazolin - administration & dosage ; Cefazolin - pharmacokinetics ; Cefazolin - therapeutic use ; Cephalosporins - administration & dosage ; Cephalosporins - pharmacokinetics ; Cephalosporins - therapeutic use ; Female ; Hallux - surgery ; Humans ; Injections, Intravenous ; Male ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Podiatry ; Surgical Wound Infection - prevention & control ; tourniquet use ; Tourniquets ; Treatment Outcome</subject><ispartof>The Journal of foot and ankle surgery, 1996-07, Vol.35 (4), p.344-349</ispartof><rights>1996 American College of Foot and Ankle Surgeons. 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The goal of prophylaxis is to prevent infection. For this to occur, there must be an adequate concentration of the antimicrobial agent in the tissue at the time of the incision. Historically, prophylaxis has consisted of intravenous administration of 1 gm. of cefazolin, 30 to 60 minutes prior to surgery. Cefazolin concentrations in the medial eminence of the first metatarsal were measured in patients undergoing bunionectomy procedures where pneumatic ankle tourniquets were used for hemostasis. The goal of this study was to determine if the current standards of prophylactic antibiotic administration provide adequate bone levels of cefazolin to effectively inhibit potential infection-causing pathogens.</description><subject>Adult</subject><subject>Antibacterial agents</subject><subject>Antibiotic Prophylaxis</subject><subject>antibiotics</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Cefazolin - administration & dosage</subject><subject>Cefazolin - pharmacokinetics</subject><subject>Cefazolin - therapeutic use</subject><subject>Cephalosporins - administration & dosage</subject><subject>Cephalosporins - pharmacokinetics</subject><subject>Cephalosporins - therapeutic use</subject><subject>Female</subject><subject>Hallux - surgery</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Podiatry</subject><subject>Surgical Wound Infection - prevention & control</subject><subject>tourniquet use</subject><subject>Tourniquets</subject><subject>Treatment Outcome</subject><issn>1067-2516</issn><issn>1542-2224</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9PwyAYh4nRzDn9CEt6MEYPVaBA4WSWxanJEg_qmVBKFdPRCtS4by_7o1dPEN7nx_vLA8AUwWsEEbt5RpCVOaaIXQp2xSHkNOcHYIwowTnGmBym-y9yDE5C-IAQY8HpCIw4L3FJxRgsZi7aynbR6qz3Xf--btW3DZlydRa7wTv7OZiYqb5vrVbRdi6zLuu72qroUyYM_s349Sk4alQbzNn-nIDXxd3L_CFfPt0_zmfLXBeQxFwViJaaFVXFCCmakjNFWM20aQRvOFK6FpSRmiNBK5FeIaZMoAZrpgXhjSkm4GL3b-qaioUoVzZo07bKmW4IsuSEcCFIAukO1L4LwZtG9t6ulF9LBOXGn9z6kxs5UjC59Sd5yk33C4ZqZeq_1F5Ymp_v5ypo1TZeOW3DH1ZgyDjECbvdYSbJ-LLGy6CtcdrU1hsdZd3Zf4r8AFF1jV8</recordid><startdate>199607</startdate><enddate>199607</enddate><creator>Deacon, Jeffery S.</creator><creator>Wertheimer, Stuart J.</creator><creator>Washington, John A.</creator><general>Elsevier Inc</general><general>Data Trace</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199607</creationdate><title>Antibiotic prophylaxis and tourniquet application in podiatric surgery</title><author>Deacon, Jeffery S. ; Wertheimer, Stuart J. ; Washington, John A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c304t-a3157c63bb6443f786a46d6cef98f81acd9564d8195b9cef025691f2c6c948fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Antibacterial agents</topic><topic>Antibiotic Prophylaxis</topic><topic>antibiotics</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Cefazolin - administration & dosage</topic><topic>Cefazolin - pharmacokinetics</topic><topic>Cefazolin - therapeutic use</topic><topic>Cephalosporins - administration & dosage</topic><topic>Cephalosporins - pharmacokinetics</topic><topic>Cephalosporins - therapeutic use</topic><topic>Female</topic><topic>Hallux - surgery</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Podiatry</topic><topic>Surgical Wound Infection - prevention & control</topic><topic>tourniquet use</topic><topic>Tourniquets</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Deacon, Jeffery S.</creatorcontrib><creatorcontrib>Wertheimer, Stuart J.</creatorcontrib><creatorcontrib>Washington, John A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of foot and ankle surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Deacon, Jeffery S.</au><au>Wertheimer, Stuart J.</au><au>Washington, John A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibiotic prophylaxis and tourniquet application in podiatric surgery</atitle><jtitle>The Journal of foot and ankle surgery</jtitle><addtitle>J Foot Ankle Surg</addtitle><date>1996-07</date><risdate>1996</risdate><volume>35</volume><issue>4</issue><spage>344</spage><epage>349</epage><pages>344-349</pages><issn>1067-2516</issn><eissn>1542-2224</eissn><abstract>The use of prophylactic antibiosis in podiatric surgery is common, especially in patients undergoing endoprosthetic procedures, major arthrodeses, lengthy procedures, or in immunocompromised patients. 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| ispartof | The Journal of foot and ankle surgery, 1996-07, Vol.35 (4), p.344-349 |
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| language | eng |
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| subjects | Adult Antibacterial agents Antibiotic Prophylaxis antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cefazolin - administration & dosage Cefazolin - pharmacokinetics Cefazolin - therapeutic use Cephalosporins - administration & dosage Cephalosporins - pharmacokinetics Cephalosporins - therapeutic use Female Hallux - surgery Humans Injections, Intravenous Male Medical sciences Middle Aged Pharmacology. Drug treatments Podiatry Surgical Wound Infection - prevention & control tourniquet use Tourniquets Treatment Outcome |
| title | Antibiotic prophylaxis and tourniquet application in podiatric surgery |
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