Sensitivity to ischemia of chronically infarcted rat hearts; effects of long-term captopril treatment

Myocardial infarction induced hypertrophy of non-infarcted myocardium, in parallel with interstitial and perivascular fibrosis and a decreased capillary density, could increase sensitivity to ischemia. The structural cardiac changes can be reversed by long-term captopril treatment. In the present st...

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Veröffentlicht in:	European journal of pharmacology 1996-03, Vol.298 (2), p.121-128
Hauptverfasser:	Kalkman, Ed A.J., Saxena, Pramod R., Schoemaker, Regien G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacology Animals Antianginal agents. Coronary vasodilator agents Biological and medical sciences Blood Flow Velocity - drug effects Captopril Captopril - therapeutic use Cardiovascular system Ischemia Ischemia - drug therapy Male Medical sciences Metabolism Myocardial infarction Myocardial Infarction - drug therapy Perfusion Pharmacology. Drug treatments Rats Rats, Wistar Remodeling Sensitivity and Specificity
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