MIN-Biopsy of Brain Tumors: Operative Technique and Histomorphological Results

Abstract MIN-biopsy is defined as an open minimal invasive biopsy, performed by microsurgical principles over a small osteoplastic trepanation or bore hole. Localization of the lesion is performed by exact calculation using the CT-topogram. Between 1993 and 1995 ten patients with unknown intracrania...

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Veröffentlicht in:Minimally invasive neurosurgery 1996-03, Vol.39 (1), p.12-16
Hauptverfasser: Scholz, M., Schwechheimer, M. K., Hardenack, M., Heuser, L., Harders, A. G.
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container_issue 1
container_start_page 12
container_title Minimally invasive neurosurgery
container_volume 39
creator Scholz, M.
Schwechheimer, M. K.
Hardenack, M.
Heuser, L.
Harders, A. G.
description Abstract MIN-biopsy is defined as an open minimal invasive biopsy, performed by microsurgical principles over a small osteoplastic trepanation or bore hole. Localization of the lesion is performed by exact calculation using the CT-topogram. Between 1993 and 1995 ten patients with unknown intracranial lesions were operated using the MIN-biopsy approach. Age ranged between 36 to 84 years (median age 57.8 years). Patients included five females and five males. Histomorphological diagnosis was possible in all cases. Histological diagnoses were glioblastoma multiforme in three patients and B-cell malignant lymphoma in four cases. Anaplastic astrocytoma was found in one case and the diagnosis of metastatic adenocarcinoma was observed in two patients. Complications or neurological deterioration were not observed. MIN-biopsy seems to be a safe procedure to arrive at exact neuropathological diagnosis of brain tumors. The procedure is compared with the established method of stereotactic biopsy by review of the literature.
doi_str_mv 10.1055/s-2008-1052208
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K.</creatorcontrib><creatorcontrib>Hardenack, M.</creatorcontrib><creatorcontrib>Heuser, L.</creatorcontrib><creatorcontrib>Harders, A. G.</creatorcontrib><title>MIN-Biopsy of Brain Tumors: Operative Technique and Histomorphological Results</title><title>Minimally invasive neurosurgery</title><addtitle>Minim Invasive Neurosurg</addtitle><description>Abstract MIN-biopsy is defined as an open minimal invasive biopsy, performed by microsurgical principles over a small osteoplastic trepanation or bore hole. Localization of the lesion is performed by exact calculation using the CT-topogram. Between 1993 and 1995 ten patients with unknown intracranial lesions were operated using the MIN-biopsy approach. Age ranged between 36 to 84 years (median age 57.8 years). Patients included five females and five males. Histomorphological diagnosis was possible in all cases. Histological diagnoses were glioblastoma multiforme in three patients and B-cell malignant lymphoma in four cases. Anaplastic astrocytoma was found in one case and the diagnosis of metastatic adenocarcinoma was observed in two patients. Complications or neurological deterioration were not observed. MIN-biopsy seems to be a safe procedure to arrive at exact neuropathological diagnosis of brain tumors. 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subjects Adult
Aged
Biological and medical sciences
Biopsy
Brain - pathology
Brain - surgery
Brain Neoplasms - pathology
Brain Neoplasms - surgery
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Microsurgery
Middle Aged
Neurosurgery
Skull, brain, vascular surgery
Stereotaxic Techniques
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tomography, X-Ray Computed
title MIN-Biopsy of Brain Tumors: Operative Technique and Histomorphological Results
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