Preferential Release of ATP and Its Extracellular Catabolism as a Source of Adenosine upon High‐ but Not Low‐Frequency Stimulation of Rat Hippocampal Slices

: The release of adenosine and ATP evoked by electrical field stimulation in rat hippocampal slices was investigated with the following two patterns of stimulation: (1) a brief, high‐frequency burst stimulation (trains of stimuli at 100 Hz for 50 ms applied every 2 s for 1 min), to mimic a long‐term...

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Veröffentlicht in:	Journal of neurochemistry 1996-11, Vol.67 (5), p.2180-2187
Hauptverfasser:	Cunha, Rodrigo A., Vizi, E. Sylvester, Ribeiro, J. Alexandre, Sebastião, Ana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	5'-Nucleotidase - antagonists & inhibitors Adenosine Adenosine - metabolism Adenosine Diphosphate - analogs & derivatives Adenosine Diphosphate - pharmacology Adenosine Triphosphate - metabolism Animals ATP Biochemistry and metabolism Biological and medical sciences Central nervous system Ectonucleotidases Electric Stimulation Energy Metabolism Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Hippocampus Hippocampus - metabolism Hippocampus - physiology In Vitro Techniques Kinetics Long-Term Potentiation Male Models, Neurological Neurons - cytology Neurons - metabolism Neurons - physiology Rats Rats, Wistar Synaptic plasticity Time Factors Tritium Vertebrates: nervous system and sense organs
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