Two Types of Apoptotic Cell Death of Rat Central Nervous System‐Derived Neuroblastoma B50 and B104 Cells: Apoptosis Induced During Proliferation and After Differentiation

: We describe here two types of apoptotic cell death observed in the rat CNS‐derived neuroblastoma B50 and B104 cells. One type was induced by dibutyryl cyclic AMP (DBcAMP) after differentiation, and the other was induced by treatment of proliferating cells with cycloheximide. When B50 and B104 cell...

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Veröffentlicht in:	Journal of neurochemistry 1996-11, Vol.67 (5), p.1856-1865
Hauptverfasser:	Honma, Naoyuki, Uchida, Atsuko, Hirose, Hiroya, Srsen, Vlastimil, Kishimoto, Takeo, Hisanaga, Shin‐ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Animals Apoptosis Apoptosis - drug effects Biological and medical sciences Bucladesine - pharmacology Cell Differentiation - drug effects Cell Division - drug effects Cell Line Cell physiology Central nervous system Central Nervous System Neoplasms Cyclic AMP Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors Cyclic AMP-Dependent Protein Kinases - metabolism Cycloheximide - pharmacology Differentiation DNA, Neoplasm - analysis Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Isoquinolines - pharmacology Kinetics Molecular and cellular biology Neurites - drug effects Neurites - physiology Neuroblastoma Neurons - cytology Neurons - drug effects Rats Sulfonamides Time Factors Tumor Cells, Cultured
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