Correlation between clonotypic T-cell receptor beta chain variable region (TCR-Vβ) gene expression and aberrant T-cell antigen expression in cutaneous T-cell lymphoma

Immunohistochemical studies can augment the clinicopathologic diagnosis of cutaneous T‐cell lymphoma (CTCL). Our goal was to determine whether a panel of 11 T‐cell receptor (TCR) beta chain variable region (Vβ) monoclonal antibodies (moAbs) could consistently identify clonal T‐cell populations withi...

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Veröffentlicht in:	Journal of cutaneous pathology 1996-08, Vol.23 (4), p.306-311
Hauptverfasser:	Finn, Daniel T., Jaworsky, Christine, Chooback, Lilian, Jensen, Pamela J., Lessin, Stuart R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Differentiation, T-Lymphocyte - biosynthesis Biological and medical sciences Biomarkers, Tumor - biosynthesis Blotting, Western Clone Cells Gene Expression - genetics Hematologic and hematopoietic diseases Humans Immunohistochemistry Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, T-Cell - metabolism Medical sciences Receptors, Antigen, T-Cell, alpha-beta - biosynthesis Receptors, Antigen, T-Cell, alpha-beta - genetics Skin Neoplasms - metabolism
Online-Zugang:	Volltext
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