Sequence analysis of the βB2-crystallin cDNA of hamster containing a domain conserved among vertebrates

The cDNA sequence of the βB2-cry was determined from hamster (Mesocricetus auratus) and compared to the corresponding genes of bovine, frog, chicken, human, mouse and rat. Multispecies comparison demonstrated high homology between the hamster, rat and mouse gene, but larger distances to man, bovine,...

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Veröffentlicht in:Gene 1996-09, Vol.174 (1), p.181-184
Hauptverfasser: Zarbalis, Konstantinos, Chatterjee, Bimal, Löster, Jana, Werner, Thomas, Graw, Jochen
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container_end_page 184
container_issue 1
container_start_page 181
container_title Gene
container_volume 174
creator Zarbalis, Konstantinos
Chatterjee, Bimal
Löster, Jana
Werner, Thomas
Graw, Jochen
description The cDNA sequence of the βB2-cry was determined from hamster (Mesocricetus auratus) and compared to the corresponding genes of bovine, frog, chicken, human, mouse and rat. Multispecies comparison demonstrated high homology between the hamster, rat and mouse gene, but larger distances to man, bovine, chicken and frog. There is striking identity within a strech of 36 deduced amino acids (aa) between the Greek key motif 3 and part of motif 4. This 36-aa domain contains a putative phosphorylation site for protein kinase C and is highly conserved among all known basic βB-Cry; however, it can neither be detected in the acidic βAnor in the γ-Cry.
doi_str_mv 10.1016/0378-1119(96)00256-9
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Amino Acid Sequence
Animals
Base Sequence
Cattle
Conserved Sequence
Cricetinae
Crystallins - genetics
DNA sequence analysis
DNA, Complementary - genetics
Evolution
Eye protein
Humans
Mesocricetus auratus
Mice
Molecular Sequence Data
Polymerase chain reaction
Rats
Sequence Alignment
Sequence Analysis, DNA
title Sequence analysis of the βB2-crystallin cDNA of hamster containing a domain conserved among vertebrates
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