The reductive half-reaction in acyl-CoA dehydrogenase from pig kidney: studies with thiaoctanoyl-CoA and oxaoctanoyl-CoA analogues

Thia- and oxaoctanoyl-CoA derivatives (substituted at the C-3 and C-4 positions) have been synthesized to prove the reductive half-reaction in the medium-chain acyl-CoA dehydrogenase from pig kidney. 3-Thiaoctanoyl-CoA binds to this flavoenzyme, forming an intense, stable, long-wavelength band (at 8...

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Veröffentlicht in:	Biochemistry (Easton) 1988-07, Vol.27 (14), p.5089-5095
Hauptverfasser:	Lau, Sze Mei, Brantley, Richard K, Thorpe, Colin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - metabolism acyl-CoA dehydrogenase Acyl-CoA Dehydrogenases - metabolism Anaerobiosis Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology kidney Kidney - enzymology Oxidoreductases Structure-Activity Relationship Swine
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