Effects of synthetic form of tracheal antimicrobial peptide on respiratory pathogens

We have synthesized a C-terminal portion of tracheal antimicrobial peptide (TAP) with 38 amino acids and tested it for efficacy on various clinical isolates of Pseudomonas aeruginosa strains from patients with cystic fibrosis and also on Aspergillus fumigatus. Our results indicate that the synthetic...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1996-03, Vol.37 (3), p.599-604
Hauptverfasser:	Lawyer, Carl, Pai, Sudha, Watabe, Misako, Bakir, Haithem, Eagleton, Lanie, Watabe, Kounosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antimicrobial Cationic Peptides Aspergillus fumigatus Aspergillus fumigatus - drug effects Aspergillus fumigatus - growth & development Biological and medical sciences Cystic Fibrosis - microbiology Escherichia coli - drug effects Escherichia coli - growth & development Humans Medical sciences Microbial Sensitivity Tests Peptide Fragments - chemical synthesis Peptide Fragments - pharmacology Peptides - chemical synthesis Peptides - pharmacology Pharmacology. Drug treatments Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - growth & development Respiratory Tract Infections - microbiology
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