Intracranial Tuberculoma: Evaluation and Treatment
We used computerized tomography (CT) to screen 83 patients with partial seizures who had 1) increased intracranial pressure; 2) evidence of systemic tuberculosis; or 3) focal neurological deficit. We found intracranial tuberculoma in 20 (24%). In addition, of 55 patients with tuberculous meningitis,...
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| Veröffentlicht in: | Clinical pediatrics 1988-10, Vol.27 (10), p.487-490 |
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| container_title | Clinical pediatrics |
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| creator | Bagga, A. Kalra, V. Ghai, O.P. |
| description | We used computerized tomography (CT) to screen 83 patients with partial seizures who had 1) increased intracranial pressure; 2) evidence of systemic tuberculosis; or 3) focal neurological deficit. We found intracranial tuberculoma in 20 (24%). In addition, of 55 patients with tuberculous meningitis, 12 had associated tuberculoma.
The image morphology on CT scans showed ring lesions (14), discs (10), and irregular coalescing masses (8). Perilesional edema frequently was present. After appropriate antitubercular therapy, clinical outcome for seizures, neurological deficit, and increased intracranial pressure was satisfactory. CT lesions regressed within 12 weeks of inauguration of medical therapy in most patients. Medical management of tuberculoma is advocated, with surgery limited to those in whom such treatment is ineffective. |
| doi_str_mv | 10.1177/000992288802701004 |
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The image morphology on CT scans showed ring lesions (14), discs (10), and irregular coalescing masses (8). Perilesional edema frequently was present. After appropriate antitubercular therapy, clinical outcome for seizures, neurological deficit, and increased intracranial pressure was satisfactory. CT lesions regressed within 12 weeks of inauguration of medical therapy in most patients. Medical management of tuberculoma is advocated, with surgery limited to those in whom such treatment is ineffective.</description><identifier>ISSN: 0009-9228</identifier><identifier>EISSN: 1938-2707</identifier><identifier>DOI: 10.1177/000992288802701004</identifier><identifier>PMID: 3168385</identifier><identifier>CODEN: CPEDAM</identifier><language>eng</language><publisher>Thousand Oaks, CA: SAGE Publications</publisher><subject>Bacterial diseases ; Biological and medical sciences ; Brain Diseases - diagnosis ; Brain Diseases - drug therapy ; Child ; Child, Preschool ; Female ; Human bacterial diseases ; Humans ; Infant ; Infectious diseases ; Male ; Medical sciences ; Prognosis ; Tomography, X-Ray Computed ; Tuberculoma - diagnosis ; Tuberculoma - drug therapy ; Tuberculosis and atypical mycobacterial infections ; Tuberculosis, Meningeal - diagnosis ; Tuberculosis, Meningeal - drug therapy</subject><ispartof>Clinical pediatrics, 1988-10, Vol.27 (10), p.487-490</ispartof><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c318t-111cd6daa0d2523228a199f1b695b2adc490b4bb4455ea9fbf64eaa161d6e9283</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000992288802701004$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000992288802701004$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6721242$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3168385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bagga, A.</creatorcontrib><creatorcontrib>Kalra, V.</creatorcontrib><creatorcontrib>Ghai, O.P.</creatorcontrib><title>Intracranial Tuberculoma: Evaluation and Treatment</title><title>Clinical pediatrics</title><addtitle>Clin Pediatr (Phila)</addtitle><description>We used computerized tomography (CT) to screen 83 patients with partial seizures who had 1) increased intracranial pressure; 2) evidence of systemic tuberculosis; or 3) focal neurological deficit. We found intracranial tuberculoma in 20 (24%). In addition, of 55 patients with tuberculous meningitis, 12 had associated tuberculoma.
The image morphology on CT scans showed ring lesions (14), discs (10), and irregular coalescing masses (8). Perilesional edema frequently was present. After appropriate antitubercular therapy, clinical outcome for seizures, neurological deficit, and increased intracranial pressure was satisfactory. CT lesions regressed within 12 weeks of inauguration of medical therapy in most patients. Medical management of tuberculoma is advocated, with surgery limited to those in whom such treatment is ineffective.</description><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Brain Diseases - diagnosis</subject><subject>Brain Diseases - drug therapy</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Prognosis</subject><subject>Tomography, X-Ray Computed</subject><subject>Tuberculoma - diagnosis</subject><subject>Tuberculoma - drug therapy</subject><subject>Tuberculosis and atypical mycobacterial infections</subject><subject>Tuberculosis, Meningeal - diagnosis</subject><subject>Tuberculosis, Meningeal - drug therapy</subject><issn>0009-9228</issn><issn>1938-2707</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1LAzEQxYMotVbvIggexNvaTJLNJkcpVQsFL_UcJtmsbNmPmnQP_vemdOlF8DQM7zfzZh4hd0CfAYpiTinVmjGlFGUFBUrFGZmC5ipLbXFOpgcgOxCX5CrGLaXAac4nZMJBKq7yKblddfuALmBXY_OwGawPbmj6Fq_JRYVN9DdjnZHP1-Vm8Z6tP95Wi5d15jiofQYArpQlIi1ZzniyQtC6Ait1bhmWTmhqhbVC5LlHXdlKCo8IEkrpNVN8Rp6Oe3eh_x583Ju2js43DXa-H6IplGCap8NnhB1BF_oYg6_MLtQthh8D1BziMH_jSEP34_bBtr48jYz_J_1x1DE6bKqUg6vjCZMFAyZYwuZHLOKXN9t-CF3K5D_jX-qOclc</recordid><startdate>19881001</startdate><enddate>19881001</enddate><creator>Bagga, A.</creator><creator>Kalra, V.</creator><creator>Ghai, O.P.</creator><general>SAGE Publications</general><general>Westminster</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19881001</creationdate><title>Intracranial Tuberculoma</title><author>Bagga, A. ; Kalra, V. ; Ghai, O.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c318t-111cd6daa0d2523228a199f1b695b2adc490b4bb4455ea9fbf64eaa161d6e9283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Brain Diseases - diagnosis</topic><topic>Brain Diseases - drug therapy</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Prognosis</topic><topic>Tomography, X-Ray Computed</topic><topic>Tuberculoma - diagnosis</topic><topic>Tuberculoma - drug therapy</topic><topic>Tuberculosis and atypical mycobacterial infections</topic><topic>Tuberculosis, Meningeal - diagnosis</topic><topic>Tuberculosis, Meningeal - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bagga, A.</creatorcontrib><creatorcontrib>Kalra, V.</creatorcontrib><creatorcontrib>Ghai, O.P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bagga, A.</au><au>Kalra, V.</au><au>Ghai, O.P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intracranial Tuberculoma: Evaluation and Treatment</atitle><jtitle>Clinical pediatrics</jtitle><addtitle>Clin Pediatr (Phila)</addtitle><date>1988-10-01</date><risdate>1988</risdate><volume>27</volume><issue>10</issue><spage>487</spage><epage>490</epage><pages>487-490</pages><issn>0009-9228</issn><eissn>1938-2707</eissn><coden>CPEDAM</coden><abstract>We used computerized tomography (CT) to screen 83 patients with partial seizures who had 1) increased intracranial pressure; 2) evidence of systemic tuberculosis; or 3) focal neurological deficit. We found intracranial tuberculoma in 20 (24%). In addition, of 55 patients with tuberculous meningitis, 12 had associated tuberculoma.
The image morphology on CT scans showed ring lesions (14), discs (10), and irregular coalescing masses (8). Perilesional edema frequently was present. After appropriate antitubercular therapy, clinical outcome for seizures, neurological deficit, and increased intracranial pressure was satisfactory. CT lesions regressed within 12 weeks of inauguration of medical therapy in most patients. Medical management of tuberculoma is advocated, with surgery limited to those in whom such treatment is ineffective.</abstract><cop>Thousand Oaks, CA</cop><pub>SAGE Publications</pub><pmid>3168385</pmid><doi>10.1177/000992288802701004</doi><tpages>4</tpages></addata></record> |
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| subjects | Bacterial diseases Biological and medical sciences Brain Diseases - diagnosis Brain Diseases - drug therapy Child Child, Preschool Female Human bacterial diseases Humans Infant Infectious diseases Male Medical sciences Prognosis Tomography, X-Ray Computed Tuberculoma - diagnosis Tuberculoma - drug therapy Tuberculosis and atypical mycobacterial infections Tuberculosis, Meningeal - diagnosis Tuberculosis, Meningeal - drug therapy |
| title | Intracranial Tuberculoma: Evaluation and Treatment |
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