The Prevalence of Asymptomatic and Unrecognized Peripheral Arterial Occlusive Disease
Background The prevalence of peripheral arterial occlusive disease (PAOD), including asymptomatic cases and cases unknown to the general practitioner (GP) was estimated in 18 884 men and women, aged 45–74 years, on the list of 18 general practice centres (GPC). Methods The study population (n = 3171...
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| Veröffentlicht in: | International journal of epidemiology 1996-04, Vol.25 (2), p.282-290 |
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| container_title | International journal of epidemiology |
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| creator | STOFFERS, HENRI E J H RINKENS, PAULA E L M KESTER, ARNOLD D M KAISER, VICTOR KNOTTNERUS, J ANDRÉ |
| description | Background The prevalence of peripheral arterial occlusive disease (PAOD), including asymptomatic cases and cases unknown to the general practitioner (GP) was estimated in 18 884 men and women, aged 45–74 years, on the list of 18 general practice centres (GPC). Methods The study population (n = 3171) consisted of a stratified sample of the total population. In the GPC data were collected on intermittent claudication (IC), peripheral pulses, vascular risk factors, cardio- and cerebrovascular disease (CCVD) and the ankle brachial systolic pressure ratio (AB ratio) and PAOD was defined as an AB ratio |
| doi_str_mv | 10.1093/ije/25.2.282 |
| format | Article |
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Methods The study population (n = 3171) consisted of a stratified sample of the total population. In the GPC data were collected on intermittent claudication (IC), peripheral pulses, vascular risk factors, cardio- and cerebrovascular disease (CCVD) and the ankle brachial systolic pressure ratio (AB ratio) and PAOD was defined as an AB ratio <0.95 on two consecutive occasions. Results were recalculated for the total population. Results The prevalence of PAOD was 6.9% (95% confidence interval [CI]: 5.7–8.2%) of which one-third (2.2%) had an AB ratio <0.75. The prevalence of IC was 6.6% (95% CI: 5.2–7.9%), a quarter of which (1.6%) met the classic WHO criteria Peripheral arterial occlusive disease did not occur significantly more often among men than among women but men suffered more often from an advanced stage of PAOD. Of all PAOD cases, 22% were symptomatic. The proportion of symptomatic cases correlated positively with higher age, male gender and lower AB ratio. Among asymptomatic PAOD cases the prevalence of concomitant CCVD was three to four times as high as in the group of subjects without PAOD. Of all PAOD cases 88% were unknown to the GP and this group mainly represented less advanced cases of atherosclerosis. However, among PAOD cases with an AB ratio <0.75, 42% were unknown to the GP. Conclusions Our data on asymptomatic and unknown PAOD cases show that GPs can still enhance their efforts towards (secondary) prevention of atherosclerosis.</description><identifier>ISSN: 0300-5771</identifier><identifier>EISSN: 1464-3685</identifier><identifier>DOI: 10.1093/ije/25.2.282</identifier><identifier>PMID: 9119553</identifier><identifier>CODEN: IJEPBF</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adult ; Aged ; Arterial Occlusive Diseases - diagnosis ; Arterial Occlusive Diseases - epidemiology ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; epidemiology ; Family Practice ; Female ; general practice ; Humans ; Intermittent claudication ; Male ; Medical sciences ; Middle Aged ; Netherlands - epidemiology ; non-invasive testing ; peripheral arterial occlusive disease ; Peripheral Vascular Diseases - diagnosis ; Peripheral Vascular Diseases - epidemiology ; Population Surveillance ; Prevalence ; Risk Factors ; Surveys and Questionnaires</subject><ispartof>International journal of epidemiology, 1996-04, Vol.25 (2), p.282-290</ispartof><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c457t-d839e182bfed72d227f1a763a331859f9c1f6afb56073389b67a48ee8fc402a63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3065046$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9119553$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>STOFFERS, HENRI E J H</creatorcontrib><creatorcontrib>RINKENS, PAULA E L M</creatorcontrib><creatorcontrib>KESTER, ARNOLD D M</creatorcontrib><creatorcontrib>KAISER, VICTOR</creatorcontrib><creatorcontrib>KNOTTNERUS, J ANDRÉ</creatorcontrib><title>The Prevalence of Asymptomatic and Unrecognized Peripheral Arterial Occlusive Disease</title><title>International journal of epidemiology</title><addtitle>Int J Epidemiol</addtitle><description>Background The prevalence of peripheral arterial occlusive disease (PAOD), including asymptomatic cases and cases unknown to the general practitioner (GP) was estimated in 18 884 men and women, aged 45–74 years, on the list of 18 general practice centres (GPC). Methods The study population (n = 3171) consisted of a stratified sample of the total population. In the GPC data were collected on intermittent claudication (IC), peripheral pulses, vascular risk factors, cardio- and cerebrovascular disease (CCVD) and the ankle brachial systolic pressure ratio (AB ratio) and PAOD was defined as an AB ratio <0.95 on two consecutive occasions. Results were recalculated for the total population. Results The prevalence of PAOD was 6.9% (95% confidence interval [CI]: 5.7–8.2%) of which one-third (2.2%) had an AB ratio <0.75. The prevalence of IC was 6.6% (95% CI: 5.2–7.9%), a quarter of which (1.6%) met the classic WHO criteria Peripheral arterial occlusive disease did not occur significantly more often among men than among women but men suffered more often from an advanced stage of PAOD. Of all PAOD cases, 22% were symptomatic. The proportion of symptomatic cases correlated positively with higher age, male gender and lower AB ratio. Among asymptomatic PAOD cases the prevalence of concomitant CCVD was three to four times as high as in the group of subjects without PAOD. Of all PAOD cases 88% were unknown to the GP and this group mainly represented less advanced cases of atherosclerosis. However, among PAOD cases with an AB ratio <0.75, 42% were unknown to the GP. Conclusions Our data on asymptomatic and unknown PAOD cases show that GPs can still enhance their efforts towards (secondary) prevention of atherosclerosis.</description><subject>Adult</subject><subject>Aged</subject><subject>Arterial Occlusive Diseases - diagnosis</subject><subject>Arterial Occlusive Diseases - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>epidemiology</subject><subject>Family Practice</subject><subject>Female</subject><subject>general practice</subject><subject>Humans</subject><subject>Intermittent claudication</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Netherlands - epidemiology</subject><subject>non-invasive testing</subject><subject>peripheral arterial occlusive disease</subject><subject>Peripheral Vascular Diseases - diagnosis</subject><subject>Peripheral Vascular Diseases - epidemiology</subject><subject>Population Surveillance</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Surveys and Questionnaires</subject><issn>0300-5771</issn><issn>1464-3685</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1rGzEQhkVpSNykt14Leyg5dR19S3s0TtIUEmKKDaEXMdaOGiX74Ujr0PTXd4ONTzPD-_AyPIR8YXTKaCUu4hNecDXlU275BzJhUstSaKs-kgkVlJbKGHZCPuX8RCmTUlbH5LhirFJKTMhq-YjFIuErNNh5LPpQzPJbuxn6FoboC-jqYtUl9P2fLv7DulhgiptHTNAUszSMx7jce99sc3zF4jJmhIxn5ChAk_Hzfp6S1fXVcn5T3t7_-Dmf3ZZeKjOUtRUVMsvXAWvDa85NYGC0ACGYVVWoPAsawlppaoSw1VobkBbRBi8pBy1Oyfmud5P6ly3mwbUxe2wa6LDfZmes5JYxM4Lfd6BPfc4Jg9uk2EJ6c4y6d4tutOi4ctyNFkf86753u26xPsB7bWP-bZ9D9tCEBJ2P-YAJqhWV7--VOyzmAf8eYkjPThthlLt5-O3Yr-WdWFwuHBP_AV6BiZk</recordid><startdate>19960401</startdate><enddate>19960401</enddate><creator>STOFFERS, HENRI E J H</creator><creator>RINKENS, PAULA E L M</creator><creator>KESTER, ARNOLD D M</creator><creator>KAISER, VICTOR</creator><creator>KNOTTNERUS, J ANDRÉ</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19960401</creationdate><title>The Prevalence of Asymptomatic and Unrecognized Peripheral Arterial Occlusive Disease</title><author>STOFFERS, HENRI E J H ; RINKENS, PAULA E L M ; KESTER, ARNOLD D M ; KAISER, VICTOR ; KNOTTNERUS, J ANDRÉ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-d839e182bfed72d227f1a763a331859f9c1f6afb56073389b67a48ee8fc402a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arterial Occlusive Diseases - diagnosis</topic><topic>Arterial Occlusive Diseases - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>epidemiology</topic><topic>Family Practice</topic><topic>Female</topic><topic>general practice</topic><topic>Humans</topic><topic>Intermittent claudication</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Netherlands - epidemiology</topic><topic>non-invasive testing</topic><topic>peripheral arterial occlusive disease</topic><topic>Peripheral Vascular Diseases - diagnosis</topic><topic>Peripheral Vascular Diseases - epidemiology</topic><topic>Population Surveillance</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>STOFFERS, HENRI E J H</creatorcontrib><creatorcontrib>RINKENS, PAULA E L M</creatorcontrib><creatorcontrib>KESTER, ARNOLD D M</creatorcontrib><creatorcontrib>KAISER, VICTOR</creatorcontrib><creatorcontrib>KNOTTNERUS, J ANDRÉ</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>STOFFERS, HENRI E J H</au><au>RINKENS, PAULA E L M</au><au>KESTER, ARNOLD D M</au><au>KAISER, VICTOR</au><au>KNOTTNERUS, J ANDRÉ</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Prevalence of Asymptomatic and Unrecognized Peripheral Arterial Occlusive Disease</atitle><jtitle>International journal of epidemiology</jtitle><addtitle>Int J Epidemiol</addtitle><date>1996-04-01</date><risdate>1996</risdate><volume>25</volume><issue>2</issue><spage>282</spage><epage>290</epage><pages>282-290</pages><issn>0300-5771</issn><eissn>1464-3685</eissn><coden>IJEPBF</coden><abstract>Background The prevalence of peripheral arterial occlusive disease (PAOD), including asymptomatic cases and cases unknown to the general practitioner (GP) was estimated in 18 884 men and women, aged 45–74 years, on the list of 18 general practice centres (GPC). Methods The study population (n = 3171) consisted of a stratified sample of the total population. In the GPC data were collected on intermittent claudication (IC), peripheral pulses, vascular risk factors, cardio- and cerebrovascular disease (CCVD) and the ankle brachial systolic pressure ratio (AB ratio) and PAOD was defined as an AB ratio <0.95 on two consecutive occasions. Results were recalculated for the total population. Results The prevalence of PAOD was 6.9% (95% confidence interval [CI]: 5.7–8.2%) of which one-third (2.2%) had an AB ratio <0.75. The prevalence of IC was 6.6% (95% CI: 5.2–7.9%), a quarter of which (1.6%) met the classic WHO criteria Peripheral arterial occlusive disease did not occur significantly more often among men than among women but men suffered more often from an advanced stage of PAOD. Of all PAOD cases, 22% were symptomatic. The proportion of symptomatic cases correlated positively with higher age, male gender and lower AB ratio. Among asymptomatic PAOD cases the prevalence of concomitant CCVD was three to four times as high as in the group of subjects without PAOD. Of all PAOD cases 88% were unknown to the GP and this group mainly represented less advanced cases of atherosclerosis. However, among PAOD cases with an AB ratio <0.75, 42% were unknown to the GP. Conclusions Our data on asymptomatic and unknown PAOD cases show that GPs can still enhance their efforts towards (secondary) prevention of atherosclerosis.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>9119553</pmid><doi>10.1093/ije/25.2.282</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Arterial Occlusive Diseases - diagnosis Arterial Occlusive Diseases - epidemiology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous epidemiology Family Practice Female general practice Humans Intermittent claudication Male Medical sciences Middle Aged Netherlands - epidemiology non-invasive testing peripheral arterial occlusive disease Peripheral Vascular Diseases - diagnosis Peripheral Vascular Diseases - epidemiology Population Surveillance Prevalence Risk Factors Surveys and Questionnaires |
| title | The Prevalence of Asymptomatic and Unrecognized Peripheral Arterial Occlusive Disease |
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