Evidence for two senescence loci on human chromosome 1

Microcell-mediated introduction of a neo-tagged human chromosome 1 (HC-1-neo) into several immortal cell lines has previously been shown to induce growth arrest and phenotypic changes indicative of replicative senescence. Somatic cell hybridization studies have localized senescence activity for immo...

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Veröffentlicht in:	Genes chromosomes & cancer 1996-05, Vol.16 (1), p.55-63
Hauptverfasser:	Vojta, P J, Futreal, P A, Annab, L A, Kato, H, Pereira-Smith, O M, Barrett, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Transformed Cellular Senescence - genetics Chromosome Fragility Chromosomes, Human, Pair 1 Clone Cells Cricetinae Humans Polymerase Chain Reaction Sequence Tagged Sites
Online-Zugang:	Volltext
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