Tachyphylaxis develops to bradykinin-induced plasma extravasation in the rat

Bradykinin, an inflammatory mediator produced from plasma kallikreins, has potent effects on vascular functions, including increasing plasma extravasation and vasodilation. Attenuation in the response (desensitization to maintained exposure or tachyphylaxis to repeated administration) to bradykinin...

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Veröffentlicht in:	Neuroscience letters 1996-04, Vol.208 (2), p.143-145
Hauptverfasser:	Miao, Frederick Jia-Pei, Khasar, Sachia G., Green, Paul G., Levine, Jon D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Volume - physiology Bradykinin - pharmacology Bradykinin-induced plasma extravasation Extravasation of Diagnostic and Therapeutic Materials - metabolism Extravasation of Diagnostic and Therapeutic Materials - physiopathology Fundamental and applied biological sciences. Psychology Homologous tachyphylaxis Inflammation Inflammation - chemically induced Knee Joint - drug effects Knee Joint - immunology Knee joint inflammation Male Molecular and cellular biology Plasma - metabolism Rats Rats, Sprague-Dawley Tachyphylaxis - physiology
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