Revascularization of the solitary kidney: A challenging problem in a high risk population
Background. Patients with significant atherosclerotic stenosis involving the artery to a solitary functioning kidney present a clinical challenge. Methods. From August 1987 through August 1995, 35 of these patients (average age, 68.4±6.9 years) were treated. Comorbid conditions included previous myo...
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Veröffentlicht in: | Surgery 1996-10, Vol.120 (4), p.732-737 |
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description | Background. Patients with significant atherosclerotic stenosis involving the artery to a solitary functioning kidney present a clinical challenge.
Methods. From August 1987 through August 1995, 35 of these patients (average age, 68.4±6.9 years) were treated. Comorbid conditions included previous myocardial infarction in 23% of the patients, congestive heart failure (CHF) in 34%, chronic obstructive pulmonary disease in 20%, and diabetes in 20%. The average creatinine level of the patients was 2.5±1.5 mg/dl. Indications for revascularization were hypertension in 86%, hypertensive crisis with CHF in 17%, and renal insufficiency in 69%. Procedures performed included 19 extraanatomic bypasses, 8 concomitant with infrarenal aortic reconstruction and 2 concomitant with thoracoabdominal aortic aneurysm repair; 1 visceral segment endarterectomy; 1 renal artery endarterectomy with reimplantation; 1 superior mesenteric to renal artery bypass; 1 aortorenal bypass; and 2 percutaneous angioplasties with staged nephrectomies.
Results. At discharge, 91% of patients had stable or improved renal function with an average creatinine level of 1.7±0.8 mg/dl. Hypertension was cured or improved in 85%. Perioperative mortality was 6%, and major morbidity was 43%, including the need for permanent (9%) and temporary (9%) dialysis, respiratory insufficiency (18%), two early reoperations, six cardiac complications, one case of gastrointestinal bleeding, and one stroke. In the follow-up period (mean duration, 39.2 months), survival has been 73%, and no additional patients have required dialysis.
Conclusions. Although significant perioperative morbidity exists in this high risk population, the long-term preservation of renal function and improvement in hypertension make solitary renal revascularization worthwhile. (Surgery 1996;120:732–737.) |
doi_str_mv | 10.1016/S0039-6060(96)80024-9 |
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Methods. From August 1987 through August 1995, 35 of these patients (average age, 68.4±6.9 years) were treated. Comorbid conditions included previous myocardial infarction in 23% of the patients, congestive heart failure (CHF) in 34%, chronic obstructive pulmonary disease in 20%, and diabetes in 20%. The average creatinine level of the patients was 2.5±1.5 mg/dl. Indications for revascularization were hypertension in 86%, hypertensive crisis with CHF in 17%, and renal insufficiency in 69%. Procedures performed included 19 extraanatomic bypasses, 8 concomitant with infrarenal aortic reconstruction and 2 concomitant with thoracoabdominal aortic aneurysm repair; 1 visceral segment endarterectomy; 1 renal artery endarterectomy with reimplantation; 1 superior mesenteric to renal artery bypass; 1 aortorenal bypass; and 2 percutaneous angioplasties with staged nephrectomies.
Results. At discharge, 91% of patients had stable or improved renal function with an average creatinine level of 1.7±0.8 mg/dl. Hypertension was cured or improved in 85%. Perioperative mortality was 6%, and major morbidity was 43%, including the need for permanent (9%) and temporary (9%) dialysis, respiratory insufficiency (18%), two early reoperations, six cardiac complications, one case of gastrointestinal bleeding, and one stroke. In the follow-up period (mean duration, 39.2 months), survival has been 73%, and no additional patients have required dialysis.
Conclusions. Although significant perioperative morbidity exists in this high risk population, the long-term preservation of renal function and improvement in hypertension make solitary renal revascularization worthwhile. (Surgery 1996;120:732–737.)</description><identifier>ISSN: 0039-6060</identifier><identifier>EISSN: 1532-7361</identifier><identifier>DOI: 10.1016/S0039-6060(96)80024-9</identifier><identifier>PMID: 8862385</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Aged ; Aged, 80 and over ; Arteriosclerosis - complications ; Arteriosclerosis - mortality ; Arteriosclerosis - surgery ; Blood Vessel Prosthesis ; Female ; Follow-Up Studies ; Humans ; Kidney Failure, Chronic - etiology ; Kidney Failure, Chronic - mortality ; Kidney Failure, Chronic - surgery ; Male ; Middle Aged ; Postoperative Complications ; Renal Artery Obstruction - complications ; Renal Artery Obstruction - mortality ; Renal Artery Obstruction - surgery ; Renal Dialysis ; Risk Factors ; Treatment Outcome</subject><ispartof>Surgery, 1996-10, Vol.120 (4), p.732-737</ispartof><rights>1996 Mosby-Year Book, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-760e09aae93b8c9d1fa4c295ef9038fb71534a7a1942c0bf633e93efd4001ce03</citedby><cites>FETCH-LOGICAL-c360t-760e09aae93b8c9d1fa4c295ef9038fb71534a7a1942c0bf633e93efd4001ce03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0039-6060(96)80024-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8862385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reilly, Jeffrey M.</creatorcontrib><creatorcontrib>Ruhin, Brain G.</creatorcontrib><creatorcontrib>Thompson, Robert W.</creatorcontrib><creatorcontrib>Allen, Brent T.</creatorcontrib><creatorcontrib>Flye, M Wayne</creatorcontrib><creatorcontrib>Anderson, Charles B.</creatorcontrib><creatorcontrib>Sicard, Gregorio A.</creatorcontrib><title>Revascularization of the solitary kidney: A challenging problem in a high risk population</title><title>Surgery</title><addtitle>Surgery</addtitle><description>Background. Patients with significant atherosclerotic stenosis involving the artery to a solitary functioning kidney present a clinical challenge.
Methods. From August 1987 through August 1995, 35 of these patients (average age, 68.4±6.9 years) were treated. Comorbid conditions included previous myocardial infarction in 23% of the patients, congestive heart failure (CHF) in 34%, chronic obstructive pulmonary disease in 20%, and diabetes in 20%. The average creatinine level of the patients was 2.5±1.5 mg/dl. Indications for revascularization were hypertension in 86%, hypertensive crisis with CHF in 17%, and renal insufficiency in 69%. Procedures performed included 19 extraanatomic bypasses, 8 concomitant with infrarenal aortic reconstruction and 2 concomitant with thoracoabdominal aortic aneurysm repair; 1 visceral segment endarterectomy; 1 renal artery endarterectomy with reimplantation; 1 superior mesenteric to renal artery bypass; 1 aortorenal bypass; and 2 percutaneous angioplasties with staged nephrectomies.
Results. At discharge, 91% of patients had stable or improved renal function with an average creatinine level of 1.7±0.8 mg/dl. Hypertension was cured or improved in 85%. Perioperative mortality was 6%, and major morbidity was 43%, including the need for permanent (9%) and temporary (9%) dialysis, respiratory insufficiency (18%), two early reoperations, six cardiac complications, one case of gastrointestinal bleeding, and one stroke. In the follow-up period (mean duration, 39.2 months), survival has been 73%, and no additional patients have required dialysis.
Conclusions. Although significant perioperative morbidity exists in this high risk population, the long-term preservation of renal function and improvement in hypertension make solitary renal revascularization worthwhile. (Surgery 1996;120:732–737.)</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arteriosclerosis - complications</subject><subject>Arteriosclerosis - mortality</subject><subject>Arteriosclerosis - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Kidney Failure, Chronic - mortality</subject><subject>Kidney Failure, Chronic - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications</subject><subject>Renal Artery Obstruction - complications</subject><subject>Renal Artery Obstruction - mortality</subject><subject>Renal Artery Obstruction - surgery</subject><subject>Renal Dialysis</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><issn>0039-6060</issn><issn>1532-7361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPwzAQhC0EKqXwEyr5hOAQWMepE3NBVcVLqoTE48DJcpxNa5omxU4rlV-P-1CvnPawM7M7HyF9BjcMmLh9B-AyEiDgSorrDCBOInlEumzA4yjlgh2T7kFySs68_wYAmbCsQzpZJmKeDbrk6w1X2ptlpZ391a1tatqUtJ0i9U1lW-3WdGaLGtd3dEjNVFcV1hNbT-jCNXmFc2prqunUTqbUWT-ji2YRsjY55-Sk1JXHi_3skc_Hh4_RczR-fXoZDceR4QLaKBWAILVGyfPMyIKVOjGxHGApgWdlnoY-iU41k0lsIC8F50GKZZEAMIPAe-Rylxs--lmib9XceoNVpWtsll6lWRLzOGZBONgJjWu8d1iqhbPz0FAxUBukaotUbXgpKdQWqZLB198fWOZzLA6uPcOwv9_tMbRcWXTKG4u1wcI6NK0qGvvPhT-n2oaq</recordid><startdate>19961001</startdate><enddate>19961001</enddate><creator>Reilly, Jeffrey M.</creator><creator>Ruhin, Brain G.</creator><creator>Thompson, Robert W.</creator><creator>Allen, Brent T.</creator><creator>Flye, M Wayne</creator><creator>Anderson, Charles B.</creator><creator>Sicard, Gregorio A.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19961001</creationdate><title>Revascularization of the solitary kidney: A challenging problem in a high risk population</title><author>Reilly, Jeffrey M. ; Ruhin, Brain G. ; Thompson, Robert W. ; Allen, Brent T. ; Flye, M Wayne ; Anderson, Charles B. ; Sicard, Gregorio A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-760e09aae93b8c9d1fa4c295ef9038fb71534a7a1942c0bf633e93efd4001ce03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arteriosclerosis - complications</topic><topic>Arteriosclerosis - mortality</topic><topic>Arteriosclerosis - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - etiology</topic><topic>Kidney Failure, Chronic - mortality</topic><topic>Kidney Failure, Chronic - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications</topic><topic>Renal Artery Obstruction - complications</topic><topic>Renal Artery Obstruction - mortality</topic><topic>Renal Artery Obstruction - surgery</topic><topic>Renal Dialysis</topic><topic>Risk Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reilly, Jeffrey M.</creatorcontrib><creatorcontrib>Ruhin, Brain G.</creatorcontrib><creatorcontrib>Thompson, Robert W.</creatorcontrib><creatorcontrib>Allen, Brent T.</creatorcontrib><creatorcontrib>Flye, M Wayne</creatorcontrib><creatorcontrib>Anderson, Charles B.</creatorcontrib><creatorcontrib>Sicard, Gregorio A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reilly, Jeffrey M.</au><au>Ruhin, Brain G.</au><au>Thompson, Robert W.</au><au>Allen, Brent T.</au><au>Flye, M Wayne</au><au>Anderson, Charles B.</au><au>Sicard, Gregorio A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Revascularization of the solitary kidney: A challenging problem in a high risk population</atitle><jtitle>Surgery</jtitle><addtitle>Surgery</addtitle><date>1996-10-01</date><risdate>1996</risdate><volume>120</volume><issue>4</issue><spage>732</spage><epage>737</epage><pages>732-737</pages><issn>0039-6060</issn><eissn>1532-7361</eissn><abstract>Background. Patients with significant atherosclerotic stenosis involving the artery to a solitary functioning kidney present a clinical challenge.
Methods. From August 1987 through August 1995, 35 of these patients (average age, 68.4±6.9 years) were treated. Comorbid conditions included previous myocardial infarction in 23% of the patients, congestive heart failure (CHF) in 34%, chronic obstructive pulmonary disease in 20%, and diabetes in 20%. The average creatinine level of the patients was 2.5±1.5 mg/dl. Indications for revascularization were hypertension in 86%, hypertensive crisis with CHF in 17%, and renal insufficiency in 69%. Procedures performed included 19 extraanatomic bypasses, 8 concomitant with infrarenal aortic reconstruction and 2 concomitant with thoracoabdominal aortic aneurysm repair; 1 visceral segment endarterectomy; 1 renal artery endarterectomy with reimplantation; 1 superior mesenteric to renal artery bypass; 1 aortorenal bypass; and 2 percutaneous angioplasties with staged nephrectomies.
Results. At discharge, 91% of patients had stable or improved renal function with an average creatinine level of 1.7±0.8 mg/dl. Hypertension was cured or improved in 85%. Perioperative mortality was 6%, and major morbidity was 43%, including the need for permanent (9%) and temporary (9%) dialysis, respiratory insufficiency (18%), two early reoperations, six cardiac complications, one case of gastrointestinal bleeding, and one stroke. In the follow-up period (mean duration, 39.2 months), survival has been 73%, and no additional patients have required dialysis.
Conclusions. Although significant perioperative morbidity exists in this high risk population, the long-term preservation of renal function and improvement in hypertension make solitary renal revascularization worthwhile. (Surgery 1996;120:732–737.)</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>8862385</pmid><doi>10.1016/S0039-6060(96)80024-9</doi><tpages>6</tpages></addata></record> |
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subjects | Aged Aged, 80 and over Arteriosclerosis - complications Arteriosclerosis - mortality Arteriosclerosis - surgery Blood Vessel Prosthesis Female Follow-Up Studies Humans Kidney Failure, Chronic - etiology Kidney Failure, Chronic - mortality Kidney Failure, Chronic - surgery Male Middle Aged Postoperative Complications Renal Artery Obstruction - complications Renal Artery Obstruction - mortality Renal Artery Obstruction - surgery Renal Dialysis Risk Factors Treatment Outcome |
title | Revascularization of the solitary kidney: A challenging problem in a high risk population |
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