The role of corticosteroids in respiratory diseases of children

Glucocorticosteroids are potent anti-inflammatory agents and have an important role in a variety of respiratory diseases. Although their exact mode of action is unknown, it is thought that they exert their effects by binding to cytoplasmic glucocorticoid receptors. In certain conditions, such as ast...

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Veröffentlicht in:Pediatric pulmonology 1996-07, Vol.22 (1), p.44-57
Hauptverfasser: de Benedictis, Fernando M., Canny, Gerard J., Levison, Henry
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container_issue 1
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container_title Pediatric pulmonology
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creator de Benedictis, Fernando M.
Canny, Gerard J.
Levison, Henry
description Glucocorticosteroids are potent anti-inflammatory agents and have an important role in a variety of respiratory diseases. Although their exact mode of action is unknown, it is thought that they exert their effects by binding to cytoplasmic glucocorticoid receptors. In certain conditions, such as asthma, the value of steroids cannot be questioned, and inhaled steroids have revolutionized management. In other situations, such as interstitial lung disease, the true role of steroids is still to be defined. In the management of diseases such as tuberculosis, the use of steroids is solely based on anecdotal experience.
doi_str_mv 10.1002/(SICI)1099-0496(199607)22:1<44::AID-PPUL7>3.0.CO;2-K
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subjects Adrenal Cortex Hormones - adverse effects
Adrenal Cortex Hormones - therapeutic use
Biological and medical sciences
Child
Child, Preschool
Humans
Medical sciences
Pharmacology. Drug treatments
Respiratory system
Respiratory Tract Diseases - diagnosis
Respiratory Tract Diseases - drug therapy
Respiratory Tract Diseases - physiopathology
title The role of corticosteroids in respiratory diseases of children
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