The role of corticosteroids in respiratory diseases of children
Glucocorticosteroids are potent anti-inflammatory agents and have an important role in a variety of respiratory diseases. Although their exact mode of action is unknown, it is thought that they exert their effects by binding to cytoplasmic glucocorticoid receptors. In certain conditions, such as ast...
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Veröffentlicht in: | Pediatric pulmonology 1996-07, Vol.22 (1), p.44-57 |
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creator | de Benedictis, Fernando M. Canny, Gerard J. Levison, Henry |
description | Glucocorticosteroids are potent anti-inflammatory agents and have an important role in a variety of respiratory diseases. Although their exact mode of action is unknown, it is thought that they exert their effects by binding to cytoplasmic glucocorticoid receptors. In certain conditions, such as asthma, the value of steroids cannot be questioned, and inhaled steroids have revolutionized management. In other situations, such as interstitial lung disease, the true role of steroids is still to be defined. In the management of diseases such as tuberculosis, the use of steroids is solely based on anecdotal experience. |
doi_str_mv | 10.1002/(SICI)1099-0496(199607)22:1<44::AID-PPUL7>3.0.CO;2-K |
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Pulmonol</addtitle><description>Glucocorticosteroids are potent anti-inflammatory agents and have an important role in a variety of respiratory diseases. Although their exact mode of action is unknown, it is thought that they exert their effects by binding to cytoplasmic glucocorticoid receptors. In certain conditions, such as asthma, the value of steroids cannot be questioned, and inhaled steroids have revolutionized management. In other situations, such as interstitial lung disease, the true role of steroids is still to be defined. In the management of diseases such as tuberculosis, the use of steroids is solely based on anecdotal experience.</description><subject>Adrenal Cortex Hormones - adverse effects</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Respiratory system</subject><subject>Respiratory Tract Diseases - diagnosis</subject><subject>Respiratory Tract Diseases - drug therapy</subject><subject>Respiratory Tract Diseases - physiopathology</subject><issn>8755-6863</issn><issn>1099-0496</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kV9v0zAUxS0EGmXwEZDygND2kOL_jssEmgKMatU6lU5IvFw5jqMZ0qbYraDfHnep8gLiydI9x-ce_4zQBcFjgjF9c_ZlWk7PCdY6x1zLM6K1xOqc0gm54HwyuZx-yG9v72bqHRvjcTl_S_PrR2g0XHiMRoUSIpeFZE_Rsxi_Y5w0TU7QSVEIWWA2Qu-X9y4LXeuyrslsF7bednHrQufrmPl1Flzc-GC2XdhntY_ORBcfrPe-rYNbP0dPGtNG9-J4nqK7Tx-X5ed8Nr-alpez3HJaqFxITZhTxlgpseacMSxMEoQlulCVSQ-zrqG0qXVtKyobLiuCBa6kNdilpqfodZ-7Cd3PnYtbWPloXduatet2EVTBiVRSJuOyN9rQxRhcA5vgVybsgWA4cAU4cIUDJjhggp4rUAoEOAdIXOGBKzDAUM6BwnWKfXncv6tWrh5CjyCT_uqom2hN2wSztj4ONkaUUoKyAc8v37r9X9X-3-xfxfpBys37XJ8-7_eQa8IPkIopAV9vrmDBb2ZiIRbwjf0B5v2uiQ</recordid><startdate>199607</startdate><enddate>199607</enddate><creator>de Benedictis, Fernando M.</creator><creator>Canny, Gerard J.</creator><creator>Levison, Henry</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199607</creationdate><title>The role of corticosteroids in respiratory diseases of children</title><author>de Benedictis, Fernando M. ; Canny, Gerard J. ; Levison, Henry</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4287-56913e7aac6609443305a2875c1987ba607cef22fd9dcb26f46b1050b6ca0e803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adrenal Cortex Hormones - adverse effects</topic><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. 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subjects | Adrenal Cortex Hormones - adverse effects Adrenal Cortex Hormones - therapeutic use Biological and medical sciences Child Child, Preschool Humans Medical sciences Pharmacology. Drug treatments Respiratory system Respiratory Tract Diseases - diagnosis Respiratory Tract Diseases - drug therapy Respiratory Tract Diseases - physiopathology |
title | The role of corticosteroids in respiratory diseases of children |
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