Thrombopoietin Modulates Platelet Activation in Vitro through Protein‐Tyrosine Phosphorylation

To determine the roles of thrombopoietin (TPO) in platelet function in vitro, we examined the effects of TPO on platelet aggregation. Although several proteins in platelets were tyrosine‐phosphorylated by TPO treatment, TPO alone was unable to induce platelet aggregation. However, the secondary wave...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 1996-07, Vol.14 (4), p.439-444
Hauptverfasser:	Kubota, Yoshitsugu, Arai, Takeshi, Tanaka, Terukazu, Yamaoka, Genji, Kiuchi, Hiroyuki, Kajikawa, Tatsushi, Kawanishi, Koichi, Ohnishi, Hiroaki, Yamaguchi, Masahiro, Takahara, Jiro, Irino, Shozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology ADP Blood Platelets - metabolism Blood Platelets - physiology Cells, Cultured Cytokine receptor c‐Mpl Genistein Humans Phosphorylation Platelet aggregation Platelet Aggregation - drug effects Proteins - metabolism Thrombopoietin Thrombopoietin - pharmacology Tyrosine - metabolism Tyrosine phosphorylation
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