The role of antepartum surveillance in the management of gastroschisis

Objective: To evaluate the perinatal morbidity and mortality of fetuses diagnosed with gastroschisis at our Fetal Diagnosis and Treatment Center. Methods: A retrospective review of a regional prenatal diagnostic center. Twenty-nine cases of gastroschisis which were diagnosed, managed, delivered and...

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Veröffentlicht in:International journal of gynecology and obstetrics 1996-02, Vol.52 (2), p.141-144
Hauptverfasser: Adair, C.D., Rosnes, J., Frye, A.H., Burrus, D.R., Nelson, L.H., Veille, J.-C.
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container_end_page 144
container_issue 2
container_start_page 141
container_title International journal of gynecology and obstetrics
container_volume 52
creator Adair, C.D.
Rosnes, J.
Frye, A.H.
Burrus, D.R.
Nelson, L.H.
Veille, J.-C.
description Objective: To evaluate the perinatal morbidity and mortality of fetuses diagnosed with gastroschisis at our Fetal Diagnosis and Treatment Center. Methods: A retrospective review of a regional prenatal diagnostic center. Twenty-nine cases of gastroschisis which were diagnosed, managed, delivered and had corrective surgeries through the Fetal Diagnosis and Treatment Center were identified from 1985 to 1994. Perinatal morbidity and mortality were reviewed. Antepartum testing schemes were reviewed when available to determine whether morbidity or mortality could have potentially been prevented. Results: Meconium occurrence, intrauterine growth retardation (IUGR) and oligohydramnios complicated 79%, 41% and 36% of the cases, respectively. The perinatal mortality of this series was 241 1000 . Significant differences in perinatal mortality were noted when fetal testing was incorporated ( 200 1000 vs. 286 1000 , P ≤ 0.001 ). Conclusion: Gastroschisis is associated with a high incidence of IUGR, meconium, oligohydramnios and high perinatal mortality. Antenatal testing appears to significantly lower perinatal mortality in pregnancies complicated by gastroschisis.
doi_str_mv 10.1016/0020-7292(95)02551-0
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Methods: A retrospective review of a regional prenatal diagnostic center. Twenty-nine cases of gastroschisis which were diagnosed, managed, delivered and had corrective surgeries through the Fetal Diagnosis and Treatment Center were identified from 1985 to 1994. Perinatal morbidity and mortality were reviewed. Antepartum testing schemes were reviewed when available to determine whether morbidity or mortality could have potentially been prevented. Results: Meconium occurrence, intrauterine growth retardation (IUGR) and oligohydramnios complicated 79%, 41% and 36% of the cases, respectively. The perinatal mortality of this series was 241 1000 . Significant differences in perinatal mortality were noted when fetal testing was incorporated ( 200 1000 vs. 286 1000 , P ≤ 0.001 ). Conclusion: Gastroschisis is associated with a high incidence of IUGR, meconium, oligohydramnios and high perinatal mortality. Antenatal testing appears to significantly lower perinatal mortality in pregnancies complicated by gastroschisis.</description><identifier>ISSN: 0020-7292</identifier><identifier>EISSN: 1879-3479</identifier><identifier>DOI: 10.1016/0020-7292(95)02551-0</identifier><identifier>PMID: 8855092</identifier><identifier>CODEN: IJGOAL</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Abdominal Muscles - abnormalities ; alpha-Fetoproteins - analysis ; Antepartum fetal surveillance ; Biological and medical sciences ; Diseases of mother, fetus and pregnancy ; Female ; Fetal Death - epidemiology ; Fetal Diseases - prevention &amp; control ; Fetal Growth Retardation - epidemiology ; Fetal Monitoring ; Gastroschisis ; Gynecology. Andrology. Obstetrics ; Humans ; Meconium - metabolism ; Medical sciences ; Oligohydramnios - epidemiology ; Pregnancy ; Pregnancy. Fetus. 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Methods: A retrospective review of a regional prenatal diagnostic center. Twenty-nine cases of gastroschisis which were diagnosed, managed, delivered and had corrective surgeries through the Fetal Diagnosis and Treatment Center were identified from 1985 to 1994. Perinatal morbidity and mortality were reviewed. Antepartum testing schemes were reviewed when available to determine whether morbidity or mortality could have potentially been prevented. Results: Meconium occurrence, intrauterine growth retardation (IUGR) and oligohydramnios complicated 79%, 41% and 36% of the cases, respectively. The perinatal mortality of this series was 241 1000 . Significant differences in perinatal mortality were noted when fetal testing was incorporated ( 200 1000 vs. 286 1000 , P ≤ 0.001 ). Conclusion: Gastroschisis is associated with a high incidence of IUGR, meconium, oligohydramnios and high perinatal mortality. Antenatal testing appears to significantly lower perinatal mortality in pregnancies complicated by gastroschisis.</description><subject>Abdominal Muscles - abnormalities</subject><subject>alpha-Fetoproteins - analysis</subject><subject>Antepartum fetal surveillance</subject><subject>Biological and medical sciences</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Fetal Death - epidemiology</subject><subject>Fetal Diseases - prevention &amp; control</subject><subject>Fetal Growth Retardation - epidemiology</subject><subject>Fetal Monitoring</subject><subject>Gastroschisis</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Meconium - metabolism</subject><subject>Medical sciences</subject><subject>Oligohydramnios - epidemiology</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. 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Placenta</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adair, C.D.</creatorcontrib><creatorcontrib>Rosnes, J.</creatorcontrib><creatorcontrib>Frye, A.H.</creatorcontrib><creatorcontrib>Burrus, D.R.</creatorcontrib><creatorcontrib>Nelson, L.H.</creatorcontrib><creatorcontrib>Veille, J.-C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adair, C.D.</au><au>Rosnes, J.</au><au>Frye, A.H.</au><au>Burrus, D.R.</au><au>Nelson, L.H.</au><au>Veille, J.-C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of antepartum surveillance in the management of gastroschisis</atitle><jtitle>International journal of gynecology and obstetrics</jtitle><addtitle>Int J Gynaecol Obstet</addtitle><date>1996-02</date><risdate>1996</risdate><volume>52</volume><issue>2</issue><spage>141</spage><epage>144</epage><pages>141-144</pages><issn>0020-7292</issn><eissn>1879-3479</eissn><coden>IJGOAL</coden><abstract>Objective: To evaluate the perinatal morbidity and mortality of fetuses diagnosed with gastroschisis at our Fetal Diagnosis and Treatment Center. 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source MEDLINE; Access via Wiley Online Library; Access via ScienceDirect (Elsevier)
subjects Abdominal Muscles - abnormalities
alpha-Fetoproteins - analysis
Antepartum fetal surveillance
Biological and medical sciences
Diseases of mother, fetus and pregnancy
Female
Fetal Death - epidemiology
Fetal Diseases - prevention & control
Fetal Growth Retardation - epidemiology
Fetal Monitoring
Gastroschisis
Gynecology. Andrology. Obstetrics
Humans
Meconium - metabolism
Medical sciences
Oligohydramnios - epidemiology
Pregnancy
Pregnancy. Fetus. Placenta
Retrospective Studies
title The role of antepartum surveillance in the management of gastroschisis
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