Conformational Aspects of an Uncharged Phosphate Analogon Built In at the Branch-point of a DNA Four-way Junction

Electrostatic interactions appear to be important in the conformation and dynamics of DNA four-way junctions. Particularly, the Coulomb repulsion between two approaching phosphate groups at the site of strand exchange is commonly supposed to have a negative influence on the thermodynamic stability o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of molecular biology 1996-09, Vol.262 (3), p.349-357
Hauptverfasser:	Pikkemaat, Jeroen A., Overmars, Franc J.J., Dreef-Tromp, C.Marijke, van den Elst, Hans, van Boom, Jacques H., Altona, Cornelis
Format:	Artikel
Sprache:	eng
Schlagworte:	coaxial stacking DNA - chemistry electrostatic interactions Holliday junction Magnetic Resonance Spectroscopy methylene-acetal linkage Models, Molecular NMR spectroscopy Nucleic Acid Conformation Oligonucleotides - chemistry Phosphorus Isotopes Protons Tritium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!