Comparison of carboxymethylcellulose vs. hydroxypropyl methylcellulose as a gonioscopic fluid

Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient...

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Veröffentlicht in:Optometry and vision science 1996-07, Vol.73 (7), p.466-472
Hauptverfasser: NGUYEN, T. P, NISHIMOTO, J. H, NAKAMURA, C. Y, DE LAND, P. N
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container_end_page 472
container_issue 7
container_start_page 466
container_title Optometry and vision science
container_volume 73
creator NGUYEN, T. P
NISHIMOTO, J. H
NAKAMURA, C. Y
DE LAND, P. N
description Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient comfort and cushioning during gonioscopy without producing blur or irritation. The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed. In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure, CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.
doi_str_mv 10.1097/00006324-199607000-00003
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source MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Ovid Autoload; EZB-FREE-00999 freely available EZB journals
subjects Adult
Anterior Chamber - anatomy & histology
Biological and medical sciences
Carboxymethylcellulose Sodium - adverse effects
Cornea - physiology
Double-Blind Method
Gonioscopy - methods
Humans
Hypromellose Derivatives
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Methylcellulose - adverse effects
Methylcellulose - analogs & derivatives
Ophthalmic Solutions
Ophthalmology
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Vision, Ocular - physiology
Visual Acuity - physiology
title Comparison of carboxymethylcellulose vs. hydroxypropyl methylcellulose as a gonioscopic fluid
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