Comparison of carboxymethylcellulose vs. hydroxypropyl methylcellulose as a gonioscopic fluid
Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient...
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Veröffentlicht in: | Optometry and vision science 1996-07, Vol.73 (7), p.466-472 |
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creator | NGUYEN, T. P NISHIMOTO, J. H NAKAMURA, C. Y DE LAND, P. N |
description | Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient comfort and cushioning during gonioscopy without producing blur or irritation.
The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution. |
doi_str_mv | 10.1097/00006324-199607000-00003 |
format | Article |
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The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.</description><identifier>ISSN: 1040-5488</identifier><identifier>EISSN: 1538-9235</identifier><identifier>DOI: 10.1097/00006324-199607000-00003</identifier><identifier>PMID: 8843126</identifier><identifier>CODEN: OVSCET</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Anterior Chamber - anatomy & histology ; Biological and medical sciences ; Carboxymethylcellulose Sodium - adverse effects ; Cornea - physiology ; Double-Blind Method ; Gonioscopy - methods ; Humans ; Hypromellose Derivatives ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Methylcellulose - adverse effects ; Methylcellulose - analogs & derivatives ; Ophthalmic Solutions ; Ophthalmology ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Vision, Ocular - physiology ; Visual Acuity - physiology</subject><ispartof>Optometry and vision science, 1996-07, Vol.73 (7), p.466-472</ispartof><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-1fbd4b712e23b813842280fa3bf9459f7e4101e46e32b32b5945e739fa0fb9083</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3170278$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8843126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>NGUYEN, T. P</creatorcontrib><creatorcontrib>NISHIMOTO, J. H</creatorcontrib><creatorcontrib>NAKAMURA, C. Y</creatorcontrib><creatorcontrib>DE LAND, P. N</creatorcontrib><title>Comparison of carboxymethylcellulose vs. hydroxypropyl methylcellulose as a gonioscopic fluid</title><title>Optometry and vision science</title><addtitle>Optom Vis Sci</addtitle><description>Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient comfort and cushioning during gonioscopy without producing blur or irritation.
The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.</description><subject>Adult</subject><subject>Anterior Chamber - anatomy & histology</subject><subject>Biological and medical sciences</subject><subject>Carboxymethylcellulose Sodium - adverse effects</subject><subject>Cornea - physiology</subject><subject>Double-Blind Method</subject><subject>Gonioscopy - methods</subject><subject>Humans</subject><subject>Hypromellose Derivatives</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Methylcellulose - adverse effects</subject><subject>Methylcellulose - analogs & derivatives</subject><subject>Ophthalmic Solutions</subject><subject>Ophthalmology</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. 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The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>8843126</pmid><doi>10.1097/00006324-199607000-00003</doi><tpages>7</tpages></addata></record> |
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source | MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Ovid Autoload; EZB-FREE-00999 freely available EZB journals |
subjects | Adult Anterior Chamber - anatomy & histology Biological and medical sciences Carboxymethylcellulose Sodium - adverse effects Cornea - physiology Double-Blind Method Gonioscopy - methods Humans Hypromellose Derivatives Investigative techniques, diagnostic techniques (general aspects) Medical sciences Methylcellulose - adverse effects Methylcellulose - analogs & derivatives Ophthalmic Solutions Ophthalmology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Vision, Ocular - physiology Visual Acuity - physiology |
title | Comparison of carboxymethylcellulose vs. hydroxypropyl methylcellulose as a gonioscopic fluid |
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