Physical Characterization of the Hydrates of Urapidil

Three hydrates of urapidil were prepared and characterized by means of differential scanning calorimetry, thermogravimetric analysis, infrared spectroscopy, X-ray powder diffraction, intrinsic dissolution rates, and solution calorimetry. The stoichiometry of the urapidil hydrates was found to be 1:5...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1988-05, Vol.77 (5), p.444-451
Hauptverfasser:	Botha, S.A., Caira, M.R., Guillory, J.K., Lötter, A.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemical Phenomena Chemistry, Physical Crystallography Differential Thermal Analysis Drug Stability General pharmacology Medical sciences Microscopy, Electron, Scanning Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Piperazines - analysis Solubility Spectrophotometry, Infrared Stereoisomerism X-Ray Diffraction
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