Impairment of bacterial clearance induced by norepinephrine infusion in rabbits

Purpose of the study was to investigate the potential influence of norepinephrine (NE) on immune functions in terms of systemic and organ-specific bacterial clearance in rabbits. To enable quantification of the clearance process, defined numbers of exogenous Escherichia coli (1.3 x 10(8) CFU) were i...

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Veröffentlicht in:	Intensive care medicine 1996-07, Vol.22 (7), p.637-643
Hauptverfasser:	KOCH, T, HELLER, S, VAN ACKERN, K, SCHIEFER, H. G, NEUHOF, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Bacteremia - immunology Bacteremia - microbiology Biological and medical sciences Disease Models, Animal Dose-Response Relationship, Drug Drug Evaluation, Preclinical Emergency and intensive care: infection, septic shock Escherichia coli Infections - immunology Escherichia coli Infections - microbiology Female Infusions, Intravenous Intensive care medicine Male Medical sciences Norepinephrine - physiology Norepinephrine - therapeutic use Rabbits Random Allocation Shock, Septic - immunology Shock, Septic - microbiology Vasoconstrictor Agents - pharmacology
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