Structure and Chromosomal Assignment of the Human S1-5 Gene (FBNL) That Is Highly Homologous to Fibrillin

The human S1-5 gene (fibrillin-like; FBNL) was originally isolated from a subtractively enriched cDNA library established from a subject with Werner syndrome (WS). We isolated genomic clones containing the entire S1-5 gene and determined its genomic structure including the exon–intron organization....

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Veröffentlicht in:	Genomics 1996-08, Vol.35 (3), p.590-592
Hauptverfasser:	Ikegawa, Shiro, Toda, Tatsushi, Okui, Keiko, Nakamura, Yusuke
Format:	Artikel
Sprache:	eng
Schlagworte:	AMINO ACID SEQUENCE Base Sequence Biological and medical sciences BIOLOGY AND MEDICINE, BASIC STUDIES Cells, Cultured Chromosome Mapping Chromosomes, Human, Pair 2 Classical genetics, quantitative genetics, hybrids COSMIDS DNA SEQUENCING DNA, Complementary DNA-CLONING Exons Fibrillins FLUORESCENCE Fundamental and applied biological sciences. Psychology Gene Expression GENE REGULATION GENES GENETIC MAPPING Genetics of eukaryotes. Biological and molecular evolution HEREDITARY DISEASES Human HUMAN CHROMOSOME 2 Humans In Situ Hybridization, Fluorescence IN-SITU HYBRIDIZATION Introns Microfilament Proteins - genetics Molecular Sequence Data NUCLEOTIDES PATIENTS STRUCTURE-ACTIVITY RELATIONSHIPS TISSUE DISTRIBUTION Werner Syndrome - genetics
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