MYOCARDIAL POSITRON TOMOGRAPHY WITH N-13 AMMONIA IN ASSESSMENT OF AORTOCORONARY BYPASS SURGERY
A total of 20 patients were examined at rest and during stress with N-13-ammonia myocardial positron emission tomography (PET) before and after aortocoronary bypass surgery in an attempt to evaluate the effect of surgery on myocardial perfusion and to predict the graft status. The PET images were di...
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| Veröffentlicht in: | JAPANESE CIRCULATION JOURNAL 1988/05/20, Vol.52(5), pp.411-416 |
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| creator | KONISHI, YUTAKA BAN, TOSHIHIKO OKAMOTO, YOSHIFUMI MATSUDA, KATSUHIKO OKABAYASHI, HITOSHI MATSUMOTO, MASAHIKO SONEDA, JUNICHI FUJIWARA, YASUNORI NISHIMURA, KAZUNOBU JINNO, KIMIO KIYOTA, YOSHIHARU TAMAKI, NAGARA YONEKURA, YOSHIHARU KOIDE, HARUTOSHI SENDA, MICHIO |
| description | A total of 20 patients were examined at rest and during stress with N-13-ammonia myocardial positron emission tomography (PET) before and after aortocoronary bypass surgery in an attempt to evaluate the effect of surgery on myocardial perfusion and to predict the graft status. The PET images were divided into anterior, septal, apical, lateral and posteroinferior segments for analysis and were evaluated as"normal"(no perfusion defects during stress and at rest), "ischemia"(stress-induced defects) and "fibrosis"(persistent defects both at rest and during stress). Approximately 90% of the segments which were ischemic before surgery became normal after surgery. Thus, ischemic changes are highly reversible, and the vessels perfusing these ischemic areas are most suitable for bypass surgery. However, most of the persistent defects failed to respond to revascularization surgery and, hence, represented irreversibly damaged myocardium. In predicting graft patency could be demonstrated by normal perfusion in postoperative images (p < 0.01) or by improved perfusion when pre- and postoperative images were compared (p < 0.01). However, graft occlusion could not be predicted reliablly. This study demonstrated that PET with N-13 ammonia was useful in the assessment of the effects of aortocoronary bypass surgery. However, this technique was not significantly superior to thallium-201 single-photon emission computed tomography for only qualitative analysis. |
| doi_str_mv | 10.1253/jcj.52.411 |
| format | Article |
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The PET images were divided into anterior, septal, apical, lateral and posteroinferior segments for analysis and were evaluated as"normal"(no perfusion defects during stress and at rest), "ischemia"(stress-induced defects) and "fibrosis"(persistent defects both at rest and during stress). Approximately 90% of the segments which were ischemic before surgery became normal after surgery. Thus, ischemic changes are highly reversible, and the vessels perfusing these ischemic areas are most suitable for bypass surgery. However, most of the persistent defects failed to respond to revascularization surgery and, hence, represented irreversibly damaged myocardium. In predicting graft patency could be demonstrated by normal perfusion in postoperative images (p < 0.01) or by improved perfusion when pre- and postoperative images were compared (p < 0.01). However, graft occlusion could not be predicted reliablly. This study demonstrated that PET with N-13 ammonia was useful in the assessment of the effects of aortocoronary bypass surgery. However, this technique was not significantly superior to thallium-201 single-photon emission computed tomography for only qualitative analysis.</description><identifier>ISSN: 0047-1828</identifier><identifier>EISSN: 1347-4839</identifier><identifier>DOI: 10.1253/jcj.52.411</identifier><identifier>PMID: 3261805</identifier><identifier>CODEN: JCIRA2</identifier><language>eng</language><publisher>Kyoto: The Japanese Circulation Society</publisher><subject>Adult ; Aged ; Ammonia ; Aortocoronary bypass surgery ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary Artery Bypass ; Coronary Circulation ; Coronary heart disease ; Evaluation Studies as Topic ; Female ; Graft patency ; Heart ; Heart - diagnostic imaging ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial perfusion imaging ; N-13 ammonia ; Nitrogen Radioisotopes ; Positron emission tomography ; Postoperative Period ; Tomography, Emission-Computed - methods</subject><ispartof>JAPANESE CIRCULATION JOURNAL, 1988/05/20, Vol.52(5), pp.411-416</ispartof><rights>Japanese Circulation Society</rights><rights>1988 INIST-CNRS</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-4a59b5c33109e27a0ae68772272010a70709f682c92421b0cfed55106241b913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7782290$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3261805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KONISHI, YUTAKA</creatorcontrib><creatorcontrib>BAN, TOSHIHIKO</creatorcontrib><creatorcontrib>OKAMOTO, YOSHIFUMI</creatorcontrib><creatorcontrib>MATSUDA, KATSUHIKO</creatorcontrib><creatorcontrib>OKABAYASHI, HITOSHI</creatorcontrib><creatorcontrib>MATSUMOTO, MASAHIKO</creatorcontrib><creatorcontrib>SONEDA, JUNICHI</creatorcontrib><creatorcontrib>FUJIWARA, YASUNORI</creatorcontrib><creatorcontrib>NISHIMURA, KAZUNOBU</creatorcontrib><creatorcontrib>JINNO, KIMIO</creatorcontrib><creatorcontrib>KIYOTA, YOSHIHARU</creatorcontrib><creatorcontrib>TAMAKI, NAGARA</creatorcontrib><creatorcontrib>YONEKURA, YOSHIHARU</creatorcontrib><creatorcontrib>KOIDE, HARUTOSHI</creatorcontrib><creatorcontrib>SENDA, MICHIO</creatorcontrib><title>MYOCARDIAL POSITRON TOMOGRAPHY WITH N-13 AMMONIA IN ASSESSMENT OF AORTOCORONARY BYPASS SURGERY</title><title>JAPANESE CIRCULATION JOURNAL</title><addtitle>JAPANESE CIRCULATION JOURNAL</addtitle><description>A total of 20 patients were examined at rest and during stress with N-13-ammonia myocardial positron emission tomography (PET) before and after aortocoronary bypass surgery in an attempt to evaluate the effect of surgery on myocardial perfusion and to predict the graft status. The PET images were divided into anterior, septal, apical, lateral and posteroinferior segments for analysis and were evaluated as"normal"(no perfusion defects during stress and at rest), "ischemia"(stress-induced defects) and "fibrosis"(persistent defects both at rest and during stress). Approximately 90% of the segments which were ischemic before surgery became normal after surgery. Thus, ischemic changes are highly reversible, and the vessels perfusing these ischemic areas are most suitable for bypass surgery. However, most of the persistent defects failed to respond to revascularization surgery and, hence, represented irreversibly damaged myocardium. In predicting graft patency could be demonstrated by normal perfusion in postoperative images (p < 0.01) or by improved perfusion when pre- and postoperative images were compared (p < 0.01). However, graft occlusion could not be predicted reliablly. This study demonstrated that PET with N-13 ammonia was useful in the assessment of the effects of aortocoronary bypass surgery. However, this technique was not significantly superior to thallium-201 single-photon emission computed tomography for only qualitative analysis.</description><subject>Adult</subject><subject>Aged</subject><subject>Ammonia</subject><subject>Aortocoronary bypass surgery</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Artery Bypass</subject><subject>Coronary Circulation</subject><subject>Coronary heart disease</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Graft patency</subject><subject>Heart</subject><subject>Heart - diagnostic imaging</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial perfusion imaging</subject><subject>N-13 ammonia</subject><subject>Nitrogen Radioisotopes</subject><subject>Positron emission tomography</subject><subject>Postoperative Period</subject><subject>Tomography, Emission-Computed - methods</subject><issn>0047-1828</issn><issn>1347-4839</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEGL2zAQRkVp2aa7vfRe0KH0UHB2JFmWfXRTb2KIrWB7WXypULRya-MkWys59N9XS0J6mRl4b2bgQ-gTgTmhnN0PZphzOg8JeYNmhIUiCGOWvEUzAD-TmMbv0QfnBgAqQs5v0A2jEYmBz9DPopWLtPqRp2u8kXXeVLLEjSzksko3qxY_5c0KlwFhOC0KWeYpzkuc1nVW10VWNlg-4FRWjVxIv5hWLf7ebjzG9WO1zKr2Dr3r9Ojsx0u_Rc1D1ixWwVou80W6DgyH8BiEmidbbhgjkFgqNGgbxUJQKigQ0AIEJF0UU5PQkJItmM4-c04goiHZJoTdoq_nsy_T4c_JuqPa9c7YcdR7ezg5JWIWCwLMi9_OopkOzk22Uy9Tv9PTX0VAvWapfJaKU-Wz9PLny9XTdmefr-olPM-_XLh2Ro_dpPemd1dNiJjSBLyWnbXBHfUve-V6OvZmtMr0kxlIEsHrX34u_v1__ltPyu7ZP1luioc</recordid><startdate>19880501</startdate><enddate>19880501</enddate><creator>KONISHI, YUTAKA</creator><creator>BAN, TOSHIHIKO</creator><creator>OKAMOTO, YOSHIFUMI</creator><creator>MATSUDA, KATSUHIKO</creator><creator>OKABAYASHI, HITOSHI</creator><creator>MATSUMOTO, MASAHIKO</creator><creator>SONEDA, JUNICHI</creator><creator>FUJIWARA, YASUNORI</creator><creator>NISHIMURA, KAZUNOBU</creator><creator>JINNO, KIMIO</creator><creator>KIYOTA, YOSHIHARU</creator><creator>TAMAKI, NAGARA</creator><creator>YONEKURA, YOSHIHARU</creator><creator>KOIDE, HARUTOSHI</creator><creator>SENDA, MICHIO</creator><general>The Japanese Circulation Society</general><general>Japanese Circulation Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19880501</creationdate><title>MYOCARDIAL POSITRON TOMOGRAPHY WITH N-13 AMMONIA IN ASSESSMENT OF AORTOCORONARY BYPASS SURGERY</title><author>KONISHI, YUTAKA ; BAN, TOSHIHIKO ; OKAMOTO, YOSHIFUMI ; MATSUDA, KATSUHIKO ; OKABAYASHI, HITOSHI ; MATSUMOTO, MASAHIKO ; SONEDA, JUNICHI ; FUJIWARA, YASUNORI ; NISHIMURA, KAZUNOBU ; JINNO, KIMIO ; KIYOTA, YOSHIHARU ; TAMAKI, NAGARA ; YONEKURA, YOSHIHARU ; KOIDE, HARUTOSHI ; SENDA, MICHIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-4a59b5c33109e27a0ae68772272010a70709f682c92421b0cfed55106241b913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Ammonia</topic><topic>Aortocoronary bypass surgery</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Artery Bypass</topic><topic>Coronary Circulation</topic><topic>Coronary heart disease</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Graft patency</topic><topic>Heart</topic><topic>Heart - diagnostic imaging</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial perfusion imaging</topic><topic>N-13 ammonia</topic><topic>Nitrogen Radioisotopes</topic><topic>Positron emission tomography</topic><topic>Postoperative Period</topic><topic>Tomography, Emission-Computed - methods</topic><toplevel>online_resources</toplevel><creatorcontrib>KONISHI, YUTAKA</creatorcontrib><creatorcontrib>BAN, TOSHIHIKO</creatorcontrib><creatorcontrib>OKAMOTO, YOSHIFUMI</creatorcontrib><creatorcontrib>MATSUDA, KATSUHIKO</creatorcontrib><creatorcontrib>OKABAYASHI, HITOSHI</creatorcontrib><creatorcontrib>MATSUMOTO, MASAHIKO</creatorcontrib><creatorcontrib>SONEDA, JUNICHI</creatorcontrib><creatorcontrib>FUJIWARA, YASUNORI</creatorcontrib><creatorcontrib>NISHIMURA, KAZUNOBU</creatorcontrib><creatorcontrib>JINNO, KIMIO</creatorcontrib><creatorcontrib>KIYOTA, YOSHIHARU</creatorcontrib><creatorcontrib>TAMAKI, NAGARA</creatorcontrib><creatorcontrib>YONEKURA, YOSHIHARU</creatorcontrib><creatorcontrib>KOIDE, HARUTOSHI</creatorcontrib><creatorcontrib>SENDA, MICHIO</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>JAPANESE CIRCULATION JOURNAL</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KONISHI, YUTAKA</au><au>BAN, TOSHIHIKO</au><au>OKAMOTO, YOSHIFUMI</au><au>MATSUDA, KATSUHIKO</au><au>OKABAYASHI, HITOSHI</au><au>MATSUMOTO, MASAHIKO</au><au>SONEDA, JUNICHI</au><au>FUJIWARA, YASUNORI</au><au>NISHIMURA, KAZUNOBU</au><au>JINNO, KIMIO</au><au>KIYOTA, YOSHIHARU</au><au>TAMAKI, NAGARA</au><au>YONEKURA, YOSHIHARU</au><au>KOIDE, HARUTOSHI</au><au>SENDA, MICHIO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MYOCARDIAL POSITRON TOMOGRAPHY WITH N-13 AMMONIA IN ASSESSMENT OF AORTOCORONARY BYPASS SURGERY</atitle><jtitle>JAPANESE CIRCULATION JOURNAL</jtitle><addtitle>JAPANESE CIRCULATION JOURNAL</addtitle><date>1988-05-01</date><risdate>1988</risdate><volume>52</volume><issue>5</issue><spage>411</spage><epage>416</epage><pages>411-416</pages><issn>0047-1828</issn><eissn>1347-4839</eissn><coden>JCIRA2</coden><abstract>A total of 20 patients were examined at rest and during stress with N-13-ammonia myocardial positron emission tomography (PET) before and after aortocoronary bypass surgery in an attempt to evaluate the effect of surgery on myocardial perfusion and to predict the graft status. The PET images were divided into anterior, septal, apical, lateral and posteroinferior segments for analysis and were evaluated as"normal"(no perfusion defects during stress and at rest), "ischemia"(stress-induced defects) and "fibrosis"(persistent defects both at rest and during stress). Approximately 90% of the segments which were ischemic before surgery became normal after surgery. Thus, ischemic changes are highly reversible, and the vessels perfusing these ischemic areas are most suitable for bypass surgery. However, most of the persistent defects failed to respond to revascularization surgery and, hence, represented irreversibly damaged myocardium. In predicting graft patency could be demonstrated by normal perfusion in postoperative images (p < 0.01) or by improved perfusion when pre- and postoperative images were compared (p < 0.01). However, graft occlusion could not be predicted reliablly. This study demonstrated that PET with N-13 ammonia was useful in the assessment of the effects of aortocoronary bypass surgery. However, this technique was not significantly superior to thallium-201 single-photon emission computed tomography for only qualitative analysis.</abstract><cop>Kyoto</cop><pub>The Japanese Circulation Society</pub><pmid>3261805</pmid><doi>10.1253/jcj.52.411</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0047-1828 |
| ispartof | JAPANESE CIRCULATION JOURNAL, 1988/05/20, Vol.52(5), pp.411-416 |
| issn | 0047-1828 1347-4839 |
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| subjects | Adult Aged Ammonia Aortocoronary bypass surgery Biological and medical sciences Cardiology. Vascular system Coronary Artery Bypass Coronary Circulation Coronary heart disease Evaluation Studies as Topic Female Graft patency Heart Heart - diagnostic imaging Humans Male Medical sciences Middle Aged Myocardial perfusion imaging N-13 ammonia Nitrogen Radioisotopes Positron emission tomography Postoperative Period Tomography, Emission-Computed - methods |
| title | MYOCARDIAL POSITRON TOMOGRAPHY WITH N-13 AMMONIA IN ASSESSMENT OF AORTOCORONARY BYPASS SURGERY |
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