Coronary vascular effects of dexmedetomidine during reactive hyperemia in the anesthetized dog

The central sympatholytic effects of alpha2-adrenergic agonists are believed to be beneficial during myocardial ischemia, but the peripheral vasoconstrictive effects are controversial. The aim of this study was to investigate the coronary vascular effects of dexmedetomidine (DM) during reactive hype...

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Veröffentlicht in:	Journal of cardiothoracic and vascular anesthesia 1996-08, Vol.10 (5), p.619-626
Hauptverfasser:	Roekaerts, Paul M.H.J., Prinzen, Frits W., de Lange, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology alpha2-adrenergic agonists Anesthesia Animals Biological and medical sciences Cardiovascular system Coronary Circulation - drug effects dexmedetomidine Dogs Female Hyperemia - physiopathology Imidazoles - pharmacology Lactic Acid - blood Male Medetomidine Medical sciences Miscellaneous myocardial ischemia Myocardial Ischemia - physiopathology Oxygen - blood Pharmacology. Drug treatments regional myocardial blood flow Vascular Resistance - drug effects
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