Treatment of peripheral arterial obstruction with streptokinase: results in arterial vs graft occlusions
A retrospective study of the efficacy of local low-dose intraarterial streptokinase for the treatment of peripheral arterial occlusion was performed in 60 cases. The results of treatment of occlusion of native arterial and arterial graft occlusions were compared. Twenty-two (73%) of 30 cases of arte...
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| Veröffentlicht in: | American journal of roentgenology (1976) 1988-09, Vol.151 (3), p.589-592 |
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| container_title | American journal of roentgenology (1976) |
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| creator | LeBolt, SA Tisnado, J Cho, , SR |
| description | A retrospective study of the efficacy of local low-dose intraarterial streptokinase for the treatment of peripheral arterial occlusion was performed in 60 cases. The results of treatment of occlusion of native arterial and arterial graft occlusions were compared. Twenty-two (73%) of 30 cases of arterial occlusion showed complete or partial angiographic resolution, compared with 16 (53%) of 30 cases of arterial graft occlusion. Ten (71%) of 14 patients with venous arterial grafts were successfully treated vs only six (38%) of 16 patients with prosthetic arterial grafts. These results suggest that streptokinase is an effective fibrinolytic agent for the treatment of arterial occlusion and arterial graft occlusion. Its effectiveness in arterial graft obstruction is comparatively low, although patients with venous grafts respond much more favorably than those with synthetic conduits. |
| doi_str_mv | 10.2214/ajr.151.3.589 |
| format | Article |
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The results of treatment of occlusion of native arterial and arterial graft occlusions were compared. Twenty-two (73%) of 30 cases of arterial occlusion showed complete or partial angiographic resolution, compared with 16 (53%) of 30 cases of arterial graft occlusion. Ten (71%) of 14 patients with venous arterial grafts were successfully treated vs only six (38%) of 16 patients with prosthetic arterial grafts. These results suggest that streptokinase is an effective fibrinolytic agent for the treatment of arterial occlusion and arterial graft occlusion. Its effectiveness in arterial graft obstruction is comparatively low, although patients with venous grafts respond much more favorably than those with synthetic conduits.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/ajr.151.3.589</identifier><identifier>PMID: 3261522</identifier><identifier>CODEN: AAJRDX</identifier><language>eng</language><publisher>Leesburg, VA: Am Roentgen Ray Soc</publisher><subject>Angiography ; Biological and medical sciences ; Blood. Blood coagulation. Reticuloendothelial system ; Graft Occlusion, Vascular - diagnostic imaging ; Graft Occlusion, Vascular - drug therapy ; Humans ; Injections, Intra-Arterial ; Leg - blood supply ; Medical sciences ; Pharmacology. Drug treatments ; Retrospective Studies ; Streptokinase - administration & dosage ; Streptokinase - adverse effects ; Streptokinase - therapeutic use ; Thrombosis - diagnostic imaging ; Thrombosis - drug therapy</subject><ispartof>American journal of roentgenology (1976), 1988-09, Vol.151 (3), p.589-592</ispartof><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-f6bf53c9fbdf9c54848f152594af29be2797f5e69e18bf97f2f6f31762c1db5a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4120,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7276308$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3261522$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LeBolt, SA</creatorcontrib><creatorcontrib>Tisnado, J</creatorcontrib><creatorcontrib>Cho, , SR</creatorcontrib><title>Treatment of peripheral arterial obstruction with streptokinase: results in arterial vs graft occlusions</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>A retrospective study of the efficacy of local low-dose intraarterial streptokinase for the treatment of peripheral arterial occlusion was performed in 60 cases. The results of treatment of occlusion of native arterial and arterial graft occlusions were compared. Twenty-two (73%) of 30 cases of arterial occlusion showed complete or partial angiographic resolution, compared with 16 (53%) of 30 cases of arterial graft occlusion. Ten (71%) of 14 patients with venous arterial grafts were successfully treated vs only six (38%) of 16 patients with prosthetic arterial grafts. These results suggest that streptokinase is an effective fibrinolytic agent for the treatment of arterial occlusion and arterial graft occlusion. Its effectiveness in arterial graft obstruction is comparatively low, although patients with venous grafts respond much more favorably than those with synthetic conduits.</description><subject>Angiography</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Graft Occlusion, Vascular - diagnostic imaging</subject><subject>Graft Occlusion, Vascular - drug therapy</subject><subject>Humans</subject><subject>Injections, Intra-Arterial</subject><subject>Leg - blood supply</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Retrospective Studies</subject><subject>Streptokinase - administration & dosage</subject><subject>Streptokinase - adverse effects</subject><subject>Streptokinase - therapeutic use</subject><subject>Thrombosis - diagnostic imaging</subject><subject>Thrombosis - drug therapy</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1v1DAQhi0EKtvCkSNSDqi3LLEdf4QbqihFqsSlSL1ZjnfcuDgfeBwi_n2NuuqePKN55vXoIeQDbfaM0fazfUx7Kuie74XuXpEdFa2sOW3pa7JruKS1bvj9W3KO-Ng0jdKdOiNnnEkqGNuR4S6BzSNMuZp9tUAKywDJxsqmXJpSzD3mtLoc5qnaQh6q0sKS599hsghfqgS4xoxVmE47f7F6SNaXTOfiimUV35E33kaE98f3gvy6_nZ3dVPf_vz-4-rrbe24Vrn2sveCu873B9850epW-3Kp6FrrWdcDU53yAmQHVPe-1MxLz6mSzNFDLyy_IJfPuUua_6yA2YwBHcRoJ5hXNEpzpaVuC1g_gy7NiAm8WVIYbfpnaGP-mzXFrClmDTfFbOE_HoPXfoTDC31UWeafjnOLzkaf7OQCvmCKKckbfbpvCA_DFhIYHG2MJZSabdtO_z0BZHWRbA</recordid><startdate>19880901</startdate><enddate>19880901</enddate><creator>LeBolt, SA</creator><creator>Tisnado, J</creator><creator>Cho, , SR</creator><general>Am Roentgen Ray Soc</general><general>American Roentgen Ray Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19880901</creationdate><title>Treatment of peripheral arterial obstruction with streptokinase: results in arterial vs graft occlusions</title><author>LeBolt, SA ; Tisnado, J ; Cho, , SR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-f6bf53c9fbdf9c54848f152594af29be2797f5e69e18bf97f2f6f31762c1db5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Angiography</topic><topic>Biological and medical sciences</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Graft Occlusion, Vascular - diagnostic imaging</topic><topic>Graft Occlusion, Vascular - drug therapy</topic><topic>Humans</topic><topic>Injections, Intra-Arterial</topic><topic>Leg - blood supply</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Retrospective Studies</topic><topic>Streptokinase - administration & dosage</topic><topic>Streptokinase - adverse effects</topic><topic>Streptokinase - therapeutic use</topic><topic>Thrombosis - diagnostic imaging</topic><topic>Thrombosis - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LeBolt, SA</creatorcontrib><creatorcontrib>Tisnado, J</creatorcontrib><creatorcontrib>Cho, , SR</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LeBolt, SA</au><au>Tisnado, J</au><au>Cho, , SR</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of peripheral arterial obstruction with streptokinase: results in arterial vs graft occlusions</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>1988-09-01</date><risdate>1988</risdate><volume>151</volume><issue>3</issue><spage>589</spage><epage>592</epage><pages>589-592</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><coden>AAJRDX</coden><abstract>A retrospective study of the efficacy of local low-dose intraarterial streptokinase for the treatment of peripheral arterial occlusion was performed in 60 cases. The results of treatment of occlusion of native arterial and arterial graft occlusions were compared. Twenty-two (73%) of 30 cases of arterial occlusion showed complete or partial angiographic resolution, compared with 16 (53%) of 30 cases of arterial graft occlusion. Ten (71%) of 14 patients with venous arterial grafts were successfully treated vs only six (38%) of 16 patients with prosthetic arterial grafts. These results suggest that streptokinase is an effective fibrinolytic agent for the treatment of arterial occlusion and arterial graft occlusion. Its effectiveness in arterial graft obstruction is comparatively low, although patients with venous grafts respond much more favorably than those with synthetic conduits.</abstract><cop>Leesburg, VA</cop><pub>Am Roentgen Ray Soc</pub><pmid>3261522</pmid><doi>10.2214/ajr.151.3.589</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0361-803X |
| ispartof | American journal of roentgenology (1976), 1988-09, Vol.151 (3), p.589-592 |
| issn | 0361-803X 1546-3141 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78378684 |
| source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
| subjects | Angiography Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Graft Occlusion, Vascular - diagnostic imaging Graft Occlusion, Vascular - drug therapy Humans Injections, Intra-Arterial Leg - blood supply Medical sciences Pharmacology. Drug treatments Retrospective Studies Streptokinase - administration & dosage Streptokinase - adverse effects Streptokinase - therapeutic use Thrombosis - diagnostic imaging Thrombosis - drug therapy |
| title | Treatment of peripheral arterial obstruction with streptokinase: results in arterial vs graft occlusions |
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