Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons
Corticostriatal projections arising from the infragranular layers of the motor and second somatosensory cortices were studied in rats after labeling small pools of neurons with biocytin. Camera lucida reconstruction of 263 fibers arising from laminae V and VI revealed that all corticostriatal projec...
Gespeichert in:
| Veröffentlicht in: | Brain research 1996-02, Vol.709 (2), p.311-315 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 315 |
|---|---|
| container_issue | 2 |
| container_start_page | 311 |
| container_title | Brain research |
| container_volume | 709 |
| creator | Lévesque, Martin Charara, Ali Gagnon, Serge Parent, André Deschênes, Martin |
| description | Corticostriatal projections arising from the infragranular layers of the motor and second somatosensory cortices were studied in rats after labeling small pools of neurons with biocytin. Camera lucida reconstruction of 263 fibers arising from laminae V and VI revealed that all corticostriatal projections derive from collaterals of lamina V cells whose main axons descend into the cerebral peduncle. In contrast, lamina VI cells do not branch upon the striatum, but upon the thalamus. Together with the results obtained in previous tracing studies, the present data raise the possibility that no neuron is exclusively corticostriatal. We therefore propose that all corticostriatal projections are collaterals given off by the axons of two types of neurons: layer V cells whose main axon project to the brainstem and/or spinal cord, and layer III cells that project to the contralateral hemisphere. |
| doi_str_mv | 10.1016/0006-8993(95)01333-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78377607</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0006899395013334</els_id><sourcerecordid>78377607</sourcerecordid><originalsourceid>FETCH-LOGICAL-c483t-649ac1dcaec59c15471e0b8091ecc556dbb15bb0d06f7dd13612ca66ea0da9393</originalsourceid><addsrcrecordid>eNqFkUFr3DAQhUVpSTdJ_0ELOpTQHpyMVrZkXQplaZpCIJekVzGWxouC10okb2n-feTsssfkJKT3zWP0HmOfBZwLEOoCAFTVGiO_meY7CCllVb9jC9HqZaWWNbxniwPykR3nfF-uUho4YkdtK6VW7YL1q5im4GKeUsAJB_6Q4j25KcQx8z7FDR_wiRL_yx0NQ-Zh5Aknjom4i8OAEyUsz7HnQxzXVcJxPSsvnv12XQzxf7E6ZR_6wtGn_XnC7i5_3a6uquub339WP68rV7dyqlRt0AnvkFxjnGhqLQi6Fowg55pG-a4TTdeBB9Vr74VUYulQKULwaKSRJ-xs51u-8bilPNlNyPPmOFLcZqtbqbUC_SYoNAgohgWsd6BLMedEvX1IYYPpyQqwcw92DtnOIVvT2JcebF3Gvuz9t92G_GFoH3zRv-51zA6HvgTnQj5gEkStl1CwHzuMSmj_AiWbXaDRkQ-ptGR9DK_v8Qy0CKVI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17010393</pqid></control><display><type>article</type><title>Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><source>MEDLINE</source><creator>Lévesque, Martin ; Charara, Ali ; Gagnon, Serge ; Parent, André ; Deschênes, Martin</creator><creatorcontrib>Lévesque, Martin ; Charara, Ali ; Gagnon, Serge ; Parent, André ; Deschênes, Martin</creatorcontrib><description>Corticostriatal projections arising from the infragranular layers of the motor and second somatosensory cortices were studied in rats after labeling small pools of neurons with biocytin. Camera lucida reconstruction of 263 fibers arising from laminae V and VI revealed that all corticostriatal projections derive from collaterals of lamina V cells whose main axons descend into the cerebral peduncle. In contrast, lamina VI cells do not branch upon the striatum, but upon the thalamus. Together with the results obtained in previous tracing studies, the present data raise the possibility that no neuron is exclusively corticostriatal. We therefore propose that all corticostriatal projections are collaterals given off by the axons of two types of neurons: layer V cells whose main axon project to the brainstem and/or spinal cord, and layer III cells that project to the contralateral hemisphere.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(95)01333-4</identifier><identifier>PMID: 8833768</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Anatomy ; Animals ; Axons - physiology ; Basal ganglia ; Biological and medical sciences ; Brain Mapping ; Central nervous system ; Corpus Striatum - cytology ; Corpus Striatum - physiology ; Corticospinal cell ; Corticothalamic cell ; Female ; Fundamental and applied biological sciences. Psychology ; Lysine - analogs & derivatives ; Male ; Motor cortex ; Motor Cortex - cytology ; Motor Cortex - physiology ; Rats ; Rats, Sprague-Dawley ; Second somatosensory cortex ; Somatosensory Cortex - cytology ; Somatosensory Cortex - physiology ; Striatum ; Synaptic Transmission ; Thalamus - physiology ; Vertebrates: nervous system and sense organs</subject><ispartof>Brain research, 1996-02, Vol.709 (2), p.311-315</ispartof><rights>1996</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-649ac1dcaec59c15471e0b8091ecc556dbb15bb0d06f7dd13612ca66ea0da9393</citedby><cites>FETCH-LOGICAL-c483t-649ac1dcaec59c15471e0b8091ecc556dbb15bb0d06f7dd13612ca66ea0da9393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0006-8993(95)01333-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3541,27915,27916,45986</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3014720$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8833768$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lévesque, Martin</creatorcontrib><creatorcontrib>Charara, Ali</creatorcontrib><creatorcontrib>Gagnon, Serge</creatorcontrib><creatorcontrib>Parent, André</creatorcontrib><creatorcontrib>Deschênes, Martin</creatorcontrib><title>Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Corticostriatal projections arising from the infragranular layers of the motor and second somatosensory cortices were studied in rats after labeling small pools of neurons with biocytin. Camera lucida reconstruction of 263 fibers arising from laminae V and VI revealed that all corticostriatal projections derive from collaterals of lamina V cells whose main axons descend into the cerebral peduncle. In contrast, lamina VI cells do not branch upon the striatum, but upon the thalamus. Together with the results obtained in previous tracing studies, the present data raise the possibility that no neuron is exclusively corticostriatal. We therefore propose that all corticostriatal projections are collaterals given off by the axons of two types of neurons: layer V cells whose main axon project to the brainstem and/or spinal cord, and layer III cells that project to the contralateral hemisphere.</description><subject>Anatomy</subject><subject>Animals</subject><subject>Axons - physiology</subject><subject>Basal ganglia</subject><subject>Biological and medical sciences</subject><subject>Brain Mapping</subject><subject>Central nervous system</subject><subject>Corpus Striatum - cytology</subject><subject>Corpus Striatum - physiology</subject><subject>Corticospinal cell</subject><subject>Corticothalamic cell</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Lysine - analogs & derivatives</subject><subject>Male</subject><subject>Motor cortex</subject><subject>Motor Cortex - cytology</subject><subject>Motor Cortex - physiology</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Second somatosensory cortex</subject><subject>Somatosensory Cortex - cytology</subject><subject>Somatosensory Cortex - physiology</subject><subject>Striatum</subject><subject>Synaptic Transmission</subject><subject>Thalamus - physiology</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFr3DAQhUVpSTdJ_0ELOpTQHpyMVrZkXQplaZpCIJekVzGWxouC10okb2n-feTsssfkJKT3zWP0HmOfBZwLEOoCAFTVGiO_meY7CCllVb9jC9HqZaWWNbxniwPykR3nfF-uUho4YkdtK6VW7YL1q5im4GKeUsAJB_6Q4j25KcQx8z7FDR_wiRL_yx0NQ-Zh5Aknjom4i8OAEyUsz7HnQxzXVcJxPSsvnv12XQzxf7E6ZR_6wtGn_XnC7i5_3a6uquub339WP68rV7dyqlRt0AnvkFxjnGhqLQi6Fowg55pG-a4TTdeBB9Vr74VUYulQKULwaKSRJ-xs51u-8bilPNlNyPPmOFLcZqtbqbUC_SYoNAgohgWsd6BLMedEvX1IYYPpyQqwcw92DtnOIVvT2JcebF3Gvuz9t92G_GFoH3zRv-51zA6HvgTnQj5gEkStl1CwHzuMSmj_AiWbXaDRkQ-ptGR9DK_v8Qy0CKVI</recordid><startdate>19960219</startdate><enddate>19960219</enddate><creator>Lévesque, Martin</creator><creator>Charara, Ali</creator><creator>Gagnon, Serge</creator><creator>Parent, André</creator><creator>Deschênes, Martin</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19960219</creationdate><title>Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons</title><author>Lévesque, Martin ; Charara, Ali ; Gagnon, Serge ; Parent, André ; Deschênes, Martin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-649ac1dcaec59c15471e0b8091ecc556dbb15bb0d06f7dd13612ca66ea0da9393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Anatomy</topic><topic>Animals</topic><topic>Axons - physiology</topic><topic>Basal ganglia</topic><topic>Biological and medical sciences</topic><topic>Brain Mapping</topic><topic>Central nervous system</topic><topic>Corpus Striatum - cytology</topic><topic>Corpus Striatum - physiology</topic><topic>Corticospinal cell</topic><topic>Corticothalamic cell</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Lysine - analogs & derivatives</topic><topic>Male</topic><topic>Motor cortex</topic><topic>Motor Cortex - cytology</topic><topic>Motor Cortex - physiology</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Second somatosensory cortex</topic><topic>Somatosensory Cortex - cytology</topic><topic>Somatosensory Cortex - physiology</topic><topic>Striatum</topic><topic>Synaptic Transmission</topic><topic>Thalamus - physiology</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lévesque, Martin</creatorcontrib><creatorcontrib>Charara, Ali</creatorcontrib><creatorcontrib>Gagnon, Serge</creatorcontrib><creatorcontrib>Parent, André</creatorcontrib><creatorcontrib>Deschênes, Martin</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lévesque, Martin</au><au>Charara, Ali</au><au>Gagnon, Serge</au><au>Parent, André</au><au>Deschênes, Martin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1996-02-19</date><risdate>1996</risdate><volume>709</volume><issue>2</issue><spage>311</spage><epage>315</epage><pages>311-315</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>Corticostriatal projections arising from the infragranular layers of the motor and second somatosensory cortices were studied in rats after labeling small pools of neurons with biocytin. Camera lucida reconstruction of 263 fibers arising from laminae V and VI revealed that all corticostriatal projections derive from collaterals of lamina V cells whose main axons descend into the cerebral peduncle. In contrast, lamina VI cells do not branch upon the striatum, but upon the thalamus. Together with the results obtained in previous tracing studies, the present data raise the possibility that no neuron is exclusively corticostriatal. We therefore propose that all corticostriatal projections are collaterals given off by the axons of two types of neurons: layer V cells whose main axon project to the brainstem and/or spinal cord, and layer III cells that project to the contralateral hemisphere.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>8833768</pmid><doi>10.1016/0006-8993(95)01333-4</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 1996-02, Vol.709 (2), p.311-315 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78377607 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Anatomy Animals Axons - physiology Basal ganglia Biological and medical sciences Brain Mapping Central nervous system Corpus Striatum - cytology Corpus Striatum - physiology Corticospinal cell Corticothalamic cell Female Fundamental and applied biological sciences. Psychology Lysine - analogs & derivatives Male Motor cortex Motor Cortex - cytology Motor Cortex - physiology Rats Rats, Sprague-Dawley Second somatosensory cortex Somatosensory Cortex - cytology Somatosensory Cortex - physiology Striatum Synaptic Transmission Thalamus - physiology Vertebrates: nervous system and sense organs |
| title | Corticostriatal projections from layer V cells in rat are collaterals of long-range corticofugal axons |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T01%3A39%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Corticostriatal%20projections%20from%20layer%20V%20cells%20in%20rat%20are%20collaterals%20of%20long-range%20corticofugal%20axons&rft.jtitle=Brain%20research&rft.au=L%C3%A9vesque,%20Martin&rft.date=1996-02-19&rft.volume=709&rft.issue=2&rft.spage=311&rft.epage=315&rft.pages=311-315&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/0006-8993(95)01333-4&rft_dat=%3Cproquest_cross%3E78377607%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17010393&rft_id=info:pmid/8833768&rft_els_id=0006899395013334&rfr_iscdi=true |