Radiosynthesis and biodistribution of the S-[ 18F]fluoroethyl analog of McN5652

[ 11C]McN5652 has been reported to exhibit favorable properties as a PET radiotracer for studying serotonin uptake sites. However, the use of this radiotracer may be limited by the short half-life of 11C. To obtain a tracer with longer physical half-life, we have synthesized the S-[ 18F]fluoroethyl...

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Veröffentlicht in:	Nuclear medicine and biology 1996-05, Vol.23 (4), p.407-412
Hauptverfasser:	Suehiro, Makiko, Greenberg, Joel H., Shiue, Chyng-Yann, Gonzalez, Carlos, Dembowski, Barry, Reivich, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analog Animals Autoradiography Biodistribution Biological and medical sciences Brain - diagnostic imaging Brain - metabolism Contrast media. Radiopharmaceuticals Fluorine Radioisotopes - chemistry Hydrocarbons, Fluorinated - chemical synthesis Hydrocarbons, Fluorinated - pharmacokinetics Isotope Labeling - methods Medical sciences Mice Pharmacology. Drug treatments Pyrroles - chemical synthesis Pyrroles - pharmacokinetics Quinolines - chemical synthesis Quinolines - pharmacokinetics Radiosynthesis S-[ 18F]Fluoroethyl Tissue Distribution Tomography, Emission-Computed
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