Evaluation of Nitric Oxide Formation from Nitrates in Pig Coronary Arteries

To clarify the hypothesis that organic nitrates are converted to nitric oxide (NO) via nitrite ion (NO2−) by glutathione S-transferase, the metabolic conversion of four nitrates was examined in pig coronary arteries and compared with that in rat liver. Nitrates caused the relaxation of the artery mu...

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Veröffentlicht in:Japanese Journal of Pharmacology 1996, Vol.71(2), pp.101-107
Hauptverfasser: Aniya, Yoko, Uehara, Naoko, Ishii, Chiho, Suenaga, Tuyoshi, Wada, Naomi, Matsuzaki, Toshihiro, Sakanashi, Matao
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Sprache:eng
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