Depletion of glutathione from brain cells in hyponatremia

Depletion of glutathione from brain cells in hyponatremia. In response to hyponatremia, brain cells extrude electrolytes and organic osmolytes, thereby minimizing brain edema. We demonstrate that rat brain is depleted of the antioxidant glutathione in response to hyponatremia and that osmotically-in...

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Veröffentlicht in:	Kidney international 1996-02, Vol.49 (2), p.470-476
Hauptverfasser:	Clark, Edward C., Thomas, Darbbie, Baer, Jane, Sterns, Richard H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Biological and medical sciences Brain - cytology Brain - metabolism Brain Chemistry - physiology Glioma Glutathione - deficiency Glutathione - metabolism Humans Hyponatremia - metabolism Male Medical sciences Metabolic diseases Miscellaneous Neuroblastoma Osmolar Concentration Other metabolic disorders Oxidative Stress - physiology Rats Rats, Sprague-Dawley Taurine - metabolism Tumor Cells, Cultured - metabolism
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