Interleukin-6 and tumor necrosis factor α levels after bisphosphonates treatment in vitro and in patients with malignancy

Bisphosphonates are potent inhibitors of bone resorption and are widely used in the treatment of bone diseases. One of the side effects of administered aminobisphosphonates is transient fever and some biological changes that are suggestive of an acute phase response. Pamidronate [(3-amino-lhydroxypr...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 1996-02, Vol.18 (2), p.133-139
Hauptverfasser:	Sauty, A., Pecherstorfer, M., Zimmer-Roth, I., Fioroni, P., Juillerat, L., Markert, M., Ludwig, H., Leuenberger, P., Burckhardt, P., Thiébaudi, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute phase reaction Aged Aged, 80 and over Biological and medical sciences Biphosphonates Bone Resorption - drug therapy C-reactive protein Clodronic Acid - therapeutic use Diphosphonates - therapeutic use Drug toxicity and drugs side effects treatment Female Follow-Up Studies Humans Ibandronic Acid Interleukin-1 Interleukin-1 - biosynthesis Interleukin-6 Interleukin-6 - metabolism Male Medical sciences Middle Aged Miscellaneous (drug allergy, mutagens, teratogens...) Neoplasms - drug therapy Neoplasms - metabolism Pamidronate Pharmacology. Drug treatments TNFα Tumor Necrosis Factor-alpha - metabolism
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