T‐cells of multiple myeloma patients triggered by the autologous mixed lymphocyte reaction suppress polyclonal immunoglobulin synthesis

To elucidate the possible role of T‐cells of patients with multiple myeloma (MM) in the suppression of polyclonal immunoglobulin synthesis. T‐cells with and without prior activation by the autologous mixed lymphocyte reaction (AMLR) were added to normal immunoglobulin (Ig)‐secreting cultures. The su...

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Veröffentlicht in:	Cancer 1988-09, Vol.62 (6), p.1124-1128
Hauptverfasser:	Lahat, Nitza, Aghai, Esther, Froom, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Cell Separation Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulin A - biosynthesis Immunoglobulin G - biosynthesis Immunoglobulin M - biosynthesis Immunoglobulinopathies Immunopathology Lymphocyte Culture Test, Mixed Medical sciences Middle Aged Monocytes - metabolism Multiple Myeloma - immunology T-Lymphocytes, Regulatory - immunology
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