Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing
Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors...
Gespeichert in:
| Veröffentlicht in: | Neuropsychologia 1988, Vol.26 (4), p.623-627 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 627 |
|---|---|
| container_issue | 4 |
| container_start_page | 623 |
| container_title | Neuropsychologia |
| container_volume | 26 |
| creator | Lee, Gregory P. Loring, David W. Flanigin, Herman F. Smith, Joseph R. Meador, Kimford J. |
| description | Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors were greater during electrical stimulation of the hippocampus contralateral to the seizure focus. These findings suggest that verbal intrusions are related to memory deficits, and that patients with cerebral disease who intrude words from an earlier portion of a learning test are likely to have bilateral cerebral dysfunction. |
| doi_str_mv | 10.1016/0028-3932(88)90118-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78356815</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0028393288901182</els_id><sourcerecordid>78356815</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-46a708199215d9dc89f1e8ebd42214be8c3926394b1e792a4b184c79252cd52f3</originalsourceid><addsrcrecordid>eNp9kU1LJDEQhoO4jOPHP1DIQRY99Jqv7k4ugsjoLgh7Wc8xnVQ7kf4y6Qj--804wxw9VaCet1I8hdA5Jb8oodUNIUwWXHF2JeW1IpTKgh2gJZU1L3hJxSFa7pEjdBzjGyFElEwu0IILUgoiluhl1YGdg7emw3H2ferM7McBjy2e14DXqTcDXvtpGq3ppxTxFEaXLET8AaHJIT_MIcUcidil4IdX3EM_hk88Q543vJ6iH63pIpzt6gl6flj9u_9dPP19_HN_91RYLqu5EJWpiaRKMVo65axULQUJjROMUdGAtFyxiivRUKgVM7lKYfOrZNaVrOUn6Od2bl7wPeW_de-jha4zA4wp6lryspK0zKDYgjaMMQZo9RR8b8KnpkRvxOqNNb2xpqXUX2I1y7GL3fzU9OD2oZ3J3L_c9U3MMttgBuvjHquUUqSuM3a7xSC7-PAQdLQeBgvOh3wI7Ub__R7_ASgulUk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78356815</pqid></control><display><type>article</type><title>Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Lee, Gregory P. ; Loring, David W. ; Flanigin, Herman F. ; Smith, Joseph R. ; Meador, Kimford J.</creator><creatorcontrib>Lee, Gregory P. ; Loring, David W. ; Flanigin, Herman F. ; Smith, Joseph R. ; Meador, Kimford J.</creatorcontrib><description>Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors were greater during electrical stimulation of the hippocampus contralateral to the seizure focus. These findings suggest that verbal intrusions are related to memory deficits, and that patients with cerebral disease who intrude words from an earlier portion of a learning test are likely to have bilateral cerebral dysfunction.</description><identifier>ISSN: 0028-3932</identifier><identifier>EISSN: 1873-3514</identifier><identifier>DOI: 10.1016/0028-3932(88)90118-2</identifier><identifier>PMID: 3405404</identifier><identifier>CODEN: NUPSA6</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adult ; Attention - physiology ; Behavioral psychophysiology ; Biological and medical sciences ; Dominance, Cerebral - physiology ; Electric Stimulation ; Epilepsy, Temporal Lobe - physiopathology ; Female ; Fundamental and applied biological sciences. Psychology ; Hippocampus - physiopathology ; Humans ; Male ; Memory - physiology ; Mental Recall - physiology ; Psychology. Psychoanalysis. Psychiatry ; Psychology. Psychophysiology ; Verbal Behavior - physiology ; Verbal Learning - physiology</subject><ispartof>Neuropsychologia, 1988, Vol.26 (4), p.623-627</ispartof><rights>1988</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-46a708199215d9dc89f1e8ebd42214be8c3926394b1e792a4b184c79252cd52f3</citedby><cites>FETCH-LOGICAL-c386t-46a708199215d9dc89f1e8ebd42214be8c3926394b1e792a4b184c79252cd52f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0028-3932(88)90118-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,4010,27904,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6999077$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3405404$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Gregory P.</creatorcontrib><creatorcontrib>Loring, David W.</creatorcontrib><creatorcontrib>Flanigin, Herman F.</creatorcontrib><creatorcontrib>Smith, Joseph R.</creatorcontrib><creatorcontrib>Meador, Kimford J.</creatorcontrib><title>Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing</title><title>Neuropsychologia</title><addtitle>Neuropsychologia</addtitle><description>Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors were greater during electrical stimulation of the hippocampus contralateral to the seizure focus. These findings suggest that verbal intrusions are related to memory deficits, and that patients with cerebral disease who intrude words from an earlier portion of a learning test are likely to have bilateral cerebral dysfunction.</description><subject>Adult</subject><subject>Attention - physiology</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Dominance, Cerebral - physiology</subject><subject>Electric Stimulation</subject><subject>Epilepsy, Temporal Lobe - physiopathology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hippocampus - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Memory - physiology</subject><subject>Mental Recall - physiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Verbal Behavior - physiology</subject><subject>Verbal Learning - physiology</subject><issn>0028-3932</issn><issn>1873-3514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1LJDEQhoO4jOPHP1DIQRY99Jqv7k4ugsjoLgh7Wc8xnVQ7kf4y6Qj--804wxw9VaCet1I8hdA5Jb8oodUNIUwWXHF2JeW1IpTKgh2gJZU1L3hJxSFa7pEjdBzjGyFElEwu0IILUgoiluhl1YGdg7emw3H2ferM7McBjy2e14DXqTcDXvtpGq3ppxTxFEaXLET8AaHJIT_MIcUcidil4IdX3EM_hk88Q543vJ6iH63pIpzt6gl6flj9u_9dPP19_HN_91RYLqu5EJWpiaRKMVo65axULQUJjROMUdGAtFyxiivRUKgVM7lKYfOrZNaVrOUn6Od2bl7wPeW_de-jha4zA4wp6lryspK0zKDYgjaMMQZo9RR8b8KnpkRvxOqNNb2xpqXUX2I1y7GL3fzU9OD2oZ3J3L_c9U3MMttgBuvjHquUUqSuM3a7xSC7-PAQdLQeBgvOh3wI7Ub__R7_ASgulUk</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>Lee, Gregory P.</creator><creator>Loring, David W.</creator><creator>Flanigin, Herman F.</creator><creator>Smith, Joseph R.</creator><creator>Meador, Kimford J.</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1988</creationdate><title>Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing</title><author>Lee, Gregory P. ; Loring, David W. ; Flanigin, Herman F. ; Smith, Joseph R. ; Meador, Kimford J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-46a708199215d9dc89f1e8ebd42214be8c3926394b1e792a4b184c79252cd52f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adult</topic><topic>Attention - physiology</topic><topic>Behavioral psychophysiology</topic><topic>Biological and medical sciences</topic><topic>Dominance, Cerebral - physiology</topic><topic>Electric Stimulation</topic><topic>Epilepsy, Temporal Lobe - physiopathology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hippocampus - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Memory - physiology</topic><topic>Mental Recall - physiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Verbal Behavior - physiology</topic><topic>Verbal Learning - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Gregory P.</creatorcontrib><creatorcontrib>Loring, David W.</creatorcontrib><creatorcontrib>Flanigin, Herman F.</creatorcontrib><creatorcontrib>Smith, Joseph R.</creatorcontrib><creatorcontrib>Meador, Kimford J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuropsychologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Gregory P.</au><au>Loring, David W.</au><au>Flanigin, Herman F.</au><au>Smith, Joseph R.</au><au>Meador, Kimford J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing</atitle><jtitle>Neuropsychologia</jtitle><addtitle>Neuropsychologia</addtitle><date>1988</date><risdate>1988</risdate><volume>26</volume><issue>4</issue><spage>623</spage><epage>627</epage><pages>623-627</pages><issn>0028-3932</issn><eissn>1873-3514</eissn><coden>NUPSA6</coden><abstract>Verbal memory testing was conducted during electrical stimulation of the human hippocampus in 12 epilepsy surgery candidates with unilateral temporal lobe seizure onset. Performance was assessed during baseline, left hippocampal stimulation and right hippocampal stimulation. Verbal intrusion errors were greater during electrical stimulation of the hippocampus contralateral to the seizure focus. These findings suggest that verbal intrusions are related to memory deficits, and that patients with cerebral disease who intrude words from an earlier portion of a learning test are likely to have bilateral cerebral dysfunction.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>3405404</pmid><doi>10.1016/0028-3932(88)90118-2</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-3932 |
| ispartof | Neuropsychologia, 1988, Vol.26 (4), p.623-627 |
| issn | 0028-3932 1873-3514 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78356815 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Attention - physiology Behavioral psychophysiology Biological and medical sciences Dominance, Cerebral - physiology Electric Stimulation Epilepsy, Temporal Lobe - physiopathology Female Fundamental and applied biological sciences. Psychology Hippocampus - physiopathology Humans Male Memory - physiology Mental Recall - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Verbal Behavior - physiology Verbal Learning - physiology |
| title | Electrical stimulation of the human hippocampus produces verbal intrusions during memory testing |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T15%3A07%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Electrical%20stimulation%20of%20the%20human%20hippocampus%20produces%20verbal%20intrusions%20during%20memory%20testing&rft.jtitle=Neuropsychologia&rft.au=Lee,%20Gregory%20P.&rft.date=1988&rft.volume=26&rft.issue=4&rft.spage=623&rft.epage=627&rft.pages=623-627&rft.issn=0028-3932&rft.eissn=1873-3514&rft.coden=NUPSA6&rft_id=info:doi/10.1016/0028-3932(88)90118-2&rft_dat=%3Cproquest_cross%3E78356815%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78356815&rft_id=info:pmid/3405404&rft_els_id=0028393288901182&rfr_iscdi=true |