Monitoring of heparin in vascular surgery
In patients heparinized for surgery on the infrarenal aorta, the degree of anticoagulation by heparin of stasis blood (taken from below the aortic clamp) was compared with that obtained in circulating blood taken from a forearm artery. A measurement of activated partial thromboplastin time (APTT) wa...
Gespeichert in:
| Veröffentlicht in: | Journal of vascular surgery 1988-08, Vol.8 (2), p.125-127 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 127 |
|---|---|
| container_issue | 2 |
| container_start_page | 125 |
| container_title | Journal of vascular surgery |
| container_volume | 8 |
| creator | Quigley, Francis G. Jamieson, Glyn G. Lloyd, John V. Faris, Irwin B. |
| description | In patients heparinized for surgery on the infrarenal aorta, the degree of anticoagulation by heparin of stasis blood (taken from below the aortic clamp) was compared with that obtained in circulating blood taken from a forearm artery. A measurement of activated partial thromboplastin time (APTT) was made on a venous blood sample taken from each patient before 5000 units of heparin was administered intravenously. Further measurements of APTT from static blood and from circulating arterial blood were made at 3, 15, 30, and 60 minutes after heparinization. Samples taken below the aortic clamp showed measurements of APTT lower than those from circulating arterial blood at 15, 30, and 60 minutes (p < 0.05 paired Wilcoxon rank sum test). Current methods for administering and monitoring heparin may not provide an adequate degree of anticoagulation in static blood during vascular surgery. The consequences, if any, of inadequate anticoagulation in vascular surgery need further study. |
| doi_str_mv | 10.1016/0741-5214(88)90398-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78353731</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0741521488903989</els_id><sourcerecordid>78353731</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3479-49e0b9f2ea9797c105bcc5507efc7e3be70b86b069d990eaefcef5fcb20224f73</originalsourceid><addsrcrecordid>eNp9kN9LwzAQgIMoc07_A4U9iOhD9dK0TfIiyPAXTHzR55Cmlxnp2pmsg_33pq7sUQhcuPvuuPsIOadwS4EWd8AzmuQpza6FuJHApEjkARlTkDwpBMhDMt4jx-QkhG8ASnPBR2TEIk0LOSY3b23j1q13zWLa2ukXrnT8T-Pb6GC6Wvtp6PwC_faUHFldBzwb4oR8Pj1-zF6S-fvz6-xhnhiWcZlkEqGUNkUtueSGQl4ak-fA0RqOrEQOpShKKGQlJaCOabS5NWUKaZpZzibkajd35dufDsNaLV0wWNe6wbYLiguWM85oBLMdaHwbgkerVt4ttd8qCqo3pPrzVX--EkL9GVIytl0M87tyidW-aVAS65dDPQrQtfW6MS7sMZ5C7zBi9zsMo4uNQ6-CcdgYrJxHs1ZV6_7f4xekD4FD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78353731</pqid></control><display><type>article</type><title>Monitoring of heparin in vascular surgery</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Quigley, Francis G. ; Jamieson, Glyn G. ; Lloyd, John V. ; Faris, Irwin B.</creator><creatorcontrib>Quigley, Francis G. ; Jamieson, Glyn G. ; Lloyd, John V. ; Faris, Irwin B.</creatorcontrib><description>In patients heparinized for surgery on the infrarenal aorta, the degree of anticoagulation by heparin of stasis blood (taken from below the aortic clamp) was compared with that obtained in circulating blood taken from a forearm artery. A measurement of activated partial thromboplastin time (APTT) was made on a venous blood sample taken from each patient before 5000 units of heparin was administered intravenously. Further measurements of APTT from static blood and from circulating arterial blood were made at 3, 15, 30, and 60 minutes after heparinization. Samples taken below the aortic clamp showed measurements of APTT lower than those from circulating arterial blood at 15, 30, and 60 minutes (p < 0.05 paired Wilcoxon rank sum test). Current methods for administering and monitoring heparin may not provide an adequate degree of anticoagulation in static blood during vascular surgery. The consequences, if any, of inadequate anticoagulation in vascular surgery need further study.</description><identifier>ISSN: 0741-5214</identifier><identifier>EISSN: 1097-6809</identifier><identifier>DOI: 10.1016/0741-5214(88)90398-9</identifier><identifier>PMID: 3398169</identifier><identifier>CODEN: JVSUES</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Aged ; Aorta, Abdominal - surgery ; Biological and medical sciences ; Blood Coagulation - drug effects ; Blood. Blood coagulation. Reticuloendothelial system ; Constriction ; Forearm - blood supply ; Hemostasis ; Heparin - therapeutic use ; Humans ; Male ; Medical sciences ; Middle Aged ; Partial Thromboplastin Time ; Pharmacology. Drug treatments ; Time Factors</subject><ispartof>Journal of vascular surgery, 1988-08, Vol.8 (2), p.125-127</ispartof><rights>1988</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3479-49e0b9f2ea9797c105bcc5507efc7e3be70b86b069d990eaefcef5fcb20224f73</citedby><cites>FETCH-LOGICAL-c3479-49e0b9f2ea9797c105bcc5507efc7e3be70b86b069d990eaefcef5fcb20224f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0741521488903989$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7201587$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3398169$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quigley, Francis G.</creatorcontrib><creatorcontrib>Jamieson, Glyn G.</creatorcontrib><creatorcontrib>Lloyd, John V.</creatorcontrib><creatorcontrib>Faris, Irwin B.</creatorcontrib><title>Monitoring of heparin in vascular surgery</title><title>Journal of vascular surgery</title><addtitle>J Vasc Surg</addtitle><description>In patients heparinized for surgery on the infrarenal aorta, the degree of anticoagulation by heparin of stasis blood (taken from below the aortic clamp) was compared with that obtained in circulating blood taken from a forearm artery. A measurement of activated partial thromboplastin time (APTT) was made on a venous blood sample taken from each patient before 5000 units of heparin was administered intravenously. Further measurements of APTT from static blood and from circulating arterial blood were made at 3, 15, 30, and 60 minutes after heparinization. Samples taken below the aortic clamp showed measurements of APTT lower than those from circulating arterial blood at 15, 30, and 60 minutes (p < 0.05 paired Wilcoxon rank sum test). Current methods for administering and monitoring heparin may not provide an adequate degree of anticoagulation in static blood during vascular surgery. The consequences, if any, of inadequate anticoagulation in vascular surgery need further study.</description><subject>Aged</subject><subject>Aorta, Abdominal - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation - drug effects</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Constriction</subject><subject>Forearm - blood supply</subject><subject>Hemostasis</subject><subject>Heparin - therapeutic use</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Partial Thromboplastin Time</subject><subject>Pharmacology. Drug treatments</subject><subject>Time Factors</subject><issn>0741-5214</issn><issn>1097-6809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN9LwzAQgIMoc07_A4U9iOhD9dK0TfIiyPAXTHzR55Cmlxnp2pmsg_33pq7sUQhcuPvuuPsIOadwS4EWd8AzmuQpza6FuJHApEjkARlTkDwpBMhDMt4jx-QkhG8ASnPBR2TEIk0LOSY3b23j1q13zWLa2ukXrnT8T-Pb6GC6Wvtp6PwC_faUHFldBzwb4oR8Pj1-zF6S-fvz6-xhnhiWcZlkEqGUNkUtueSGQl4ak-fA0RqOrEQOpShKKGQlJaCOabS5NWUKaZpZzibkajd35dufDsNaLV0wWNe6wbYLiguWM85oBLMdaHwbgkerVt4ttd8qCqo3pPrzVX--EkL9GVIytl0M87tyidW-aVAS65dDPQrQtfW6MS7sMZ5C7zBi9zsMo4uNQ6-CcdgYrJxHs1ZV6_7f4xekD4FD</recordid><startdate>198808</startdate><enddate>198808</enddate><creator>Quigley, Francis G.</creator><creator>Jamieson, Glyn G.</creator><creator>Lloyd, John V.</creator><creator>Faris, Irwin B.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198808</creationdate><title>Monitoring of heparin in vascular surgery</title><author>Quigley, Francis G. ; Jamieson, Glyn G. ; Lloyd, John V. ; Faris, Irwin B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3479-49e0b9f2ea9797c105bcc5507efc7e3be70b86b069d990eaefcef5fcb20224f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Aged</topic><topic>Aorta, Abdominal - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation - drug effects</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Constriction</topic><topic>Forearm - blood supply</topic><topic>Hemostasis</topic><topic>Heparin - therapeutic use</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Partial Thromboplastin Time</topic><topic>Pharmacology. Drug treatments</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Quigley, Francis G.</creatorcontrib><creatorcontrib>Jamieson, Glyn G.</creatorcontrib><creatorcontrib>Lloyd, John V.</creatorcontrib><creatorcontrib>Faris, Irwin B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quigley, Francis G.</au><au>Jamieson, Glyn G.</au><au>Lloyd, John V.</au><au>Faris, Irwin B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monitoring of heparin in vascular surgery</atitle><jtitle>Journal of vascular surgery</jtitle><addtitle>J Vasc Surg</addtitle><date>1988-08</date><risdate>1988</risdate><volume>8</volume><issue>2</issue><spage>125</spage><epage>127</epage><pages>125-127</pages><issn>0741-5214</issn><eissn>1097-6809</eissn><coden>JVSUES</coden><abstract>In patients heparinized for surgery on the infrarenal aorta, the degree of anticoagulation by heparin of stasis blood (taken from below the aortic clamp) was compared with that obtained in circulating blood taken from a forearm artery. A measurement of activated partial thromboplastin time (APTT) was made on a venous blood sample taken from each patient before 5000 units of heparin was administered intravenously. Further measurements of APTT from static blood and from circulating arterial blood were made at 3, 15, 30, and 60 minutes after heparinization. Samples taken below the aortic clamp showed measurements of APTT lower than those from circulating arterial blood at 15, 30, and 60 minutes (p < 0.05 paired Wilcoxon rank sum test). Current methods for administering and monitoring heparin may not provide an adequate degree of anticoagulation in static blood during vascular surgery. The consequences, if any, of inadequate anticoagulation in vascular surgery need further study.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>3398169</pmid><doi>10.1016/0741-5214(88)90398-9</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0741-5214 |
| ispartof | Journal of vascular surgery, 1988-08, Vol.8 (2), p.125-127 |
| issn | 0741-5214 1097-6809 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78353731 |
| source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Aorta, Abdominal - surgery Biological and medical sciences Blood Coagulation - drug effects Blood. Blood coagulation. Reticuloendothelial system Constriction Forearm - blood supply Hemostasis Heparin - therapeutic use Humans Male Medical sciences Middle Aged Partial Thromboplastin Time Pharmacology. Drug treatments Time Factors |
| title | Monitoring of heparin in vascular surgery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T17%3A48%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Monitoring%20of%20heparin%20in%20vascular%20surgery&rft.jtitle=Journal%20of%20vascular%20surgery&rft.au=Quigley,%20Francis%20G.&rft.date=1988-08&rft.volume=8&rft.issue=2&rft.spage=125&rft.epage=127&rft.pages=125-127&rft.issn=0741-5214&rft.eissn=1097-6809&rft.coden=JVSUES&rft_id=info:doi/10.1016/0741-5214(88)90398-9&rft_dat=%3Cproquest_cross%3E78353731%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78353731&rft_id=info:pmid/3398169&rft_els_id=0741521488903989&rfr_iscdi=true |