Activation of B lymphocytes: integrating signals from CD19, CD22 and FcγRIIb1

Three accessory membrane proteins, CD19, CD22 and FcγRIIb1, alter signaling through membrane immunoglobulin of B cells by binding cytosolic proteins containing SH2 domains. Recent biochemical and genetic studies have shown that these receptors enable B cells to amplify responses to certain T-cell-de...

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Veröffentlicht in:	Current opinion in immunology 1996-06, Vol.8 (3), p.378-382
Hauptverfasser:	Doody, Gina M, Dempsey, Paul W, Fearon, Douglas T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - physiology Antigens, CD19 - physiology Antigens, Differentiation, B-Lymphocyte - physiology B-Lymphocytes - immunology Cell Adhesion Molecules Humans Lectins Lymphocyte Activation Receptors, IgG - physiology Sialic Acid Binding Ig-like Lectin 2 Signal Transduction - immunology
Online-Zugang:	Volltext
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