Polyclonal B-Cell activation by Neisseria meningitidis capsular polysaccharides elicit antibodies protective against Trypanosoma cruzi infection in vitro

A hyperimmune rabbit antiserum against group C Neisseria meningitidis agglutinated and lysed Trypanosoma cruzi metacyclic trypomastigotes in a complement‐mediated reaction. Immunization of rabbits with the purified polysaccharide C from N. meningitidis and of human volunteers with the AC‐polysacchar...

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Veröffentlicht in:	Journal of clinical laboratory analysis 1996, Vol.10 (4), p.220-228
Hauptverfasser:	Oliveira, Teresa G., Milani, Sandra R., Travassos, Luiz R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Bacterial - immunology B-Lymphocytes - immunology Bacterial Capsules - immunology Chagas disease Chagas Disease - prevention & control Enzyme-Linked Immunosorbent Assay - methods HeLa Cells - parasitology Humans Lymphocyte Activation - immunology Male meningococcal AC-vaccine Neisseria meningitidis Neisseria meningitidis - immunology polyclonal activation polysaccharide C Polysaccharides, Bacterial - immunology Rabbits Serologic Tests - methods sialic acids Trypanosoma cruzi Trypanosoma cruzi - isolation & purification trypomastigotes
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