Eosinophilic Endomyometritis Associated with Diagnostic Curettage
SUMMARYHistological study of hysterectomy specimens removed for noninflammatory and nonneoplastic disease revealed 15 severe cases and many more slight cases of eosinophil leukocytic endomyometritis, the degree of which appeared to correlate with injury from preoperative diagnostic curettage. In eac...
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| Veröffentlicht in: | International journal of gynecological pathology 1988-05, Vol.7 (2), p.162-172 |
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| container_title | International journal of gynecological pathology |
| container_volume | 7 |
| creator | Mikó, Tivadar L Lampé, László G Thomázy, Vilmos A Molnár, Péter Endes, Pongrác |
| description | SUMMARYHistological study of hysterectomy specimens removed for noninflammatory and nonneoplastic disease revealed 15 severe cases and many more slight cases of eosinophil leukocytic endomyometritis, the degree of which appeared to correlate with injury from preoperative diagnostic curettage. In each case of severe eosinophitic endomyometritis, circumferential mucosal and extensive myometrial damage together with an occluding blood clot at the level of the inner orifice was confirmed. The massive eosinophilia appeared any time between 18 h and 21 days after curettage, and it is proposed that the probable causative agents are eosinophil chemotactic substances liberated from the myometrial mast cells and from the degrading blood clot filling the uterine cavity. There were no clinical signs or symptoms that appeared to correlate with the histological changes observed in this study. This phenomenon may serve as a model for studying the dynamics and functions of eosinophilic leukocytes in humans. |
| doi_str_mv | 10.1097/00004347-198805000-00007 |
| format | Article |
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In each case of severe eosinophitic endomyometritis, circumferential mucosal and extensive myometrial damage together with an occluding blood clot at the level of the inner orifice was confirmed. The massive eosinophilia appeared any time between 18 h and 21 days after curettage, and it is proposed that the probable causative agents are eosinophil chemotactic substances liberated from the myometrial mast cells and from the degrading blood clot filling the uterine cavity. There were no clinical signs or symptoms that appeared to correlate with the histological changes observed in this study. This phenomenon may serve as a model for studying the dynamics and functions of eosinophilic leukocytes in humans.</description><identifier>ISSN: 0277-1691</identifier><identifier>EISSN: 1538-7151</identifier><identifier>DOI: 10.1097/00004347-198805000-00007</identifier><identifier>PMID: 3397210</identifier><identifier>CODEN: IJGPDR</identifier><language>eng</language><publisher>Philadelphia, PA: International Society of Gynecological Pathologists</publisher><subject>Aged ; Biological and medical sciences ; Dilatation and Curettage - adverse effects ; Endometritis - etiology ; Endometritis - pathology ; Eosinophilia - etiology ; Eosinophilia - pathology ; Eosinophils - ultrastructure ; Female ; Female genital diseases ; Gynecology. Andrology. Obstetrics ; Humans ; Hysterectomy ; Mast Cells - ultrastructure ; Medical sciences ; Microscopy, Electron ; Middle Aged ; Myometrium - injuries ; Non tumoral diseases</subject><ispartof>International journal of gynecological pathology, 1988-05, Vol.7 (2), p.162-172</ispartof><rights>1988International Society of Gynecological Pathologists</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3847-4b6575d64f3b58e486342ffdf473a02d3ef734e311781615c75dbdd5c84d80ff3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7293586$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3397210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mikó, Tivadar L</creatorcontrib><creatorcontrib>Lampé, László G</creatorcontrib><creatorcontrib>Thomázy, Vilmos A</creatorcontrib><creatorcontrib>Molnár, Péter</creatorcontrib><creatorcontrib>Endes, Pongrác</creatorcontrib><title>Eosinophilic Endomyometritis Associated with Diagnostic Curettage</title><title>International journal of gynecological pathology</title><addtitle>Int J Gynecol Pathol</addtitle><description>SUMMARYHistological study of hysterectomy specimens removed for noninflammatory and nonneoplastic disease revealed 15 severe cases and many more slight cases of eosinophil leukocytic endomyometritis, the degree of which appeared to correlate with injury from preoperative diagnostic curettage. In each case of severe eosinophitic endomyometritis, circumferential mucosal and extensive myometrial damage together with an occluding blood clot at the level of the inner orifice was confirmed. The massive eosinophilia appeared any time between 18 h and 21 days after curettage, and it is proposed that the probable causative agents are eosinophil chemotactic substances liberated from the myometrial mast cells and from the degrading blood clot filling the uterine cavity. There were no clinical signs or symptoms that appeared to correlate with the histological changes observed in this study. This phenomenon may serve as a model for studying the dynamics and functions of eosinophilic leukocytes in humans.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Dilatation and Curettage - adverse effects</subject><subject>Endometritis - etiology</subject><subject>Endometritis - pathology</subject><subject>Eosinophilia - etiology</subject><subject>Eosinophilia - pathology</subject><subject>Eosinophils - ultrastructure</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Mast Cells - ultrastructure</subject><subject>Medical sciences</subject><subject>Microscopy, Electron</subject><subject>Middle Aged</subject><subject>Myometrium - injuries</subject><subject>Non tumoral diseases</subject><issn>0277-1691</issn><issn>1538-7151</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1PAyEQhonR1Fr9CSZ7MN5WYYGFPTa1fiRNvOiZUD4surtUYNP030tt7c25TGbmmWF4B4ACwTsEG3YPsxFMWIkaziHNUblLsRMwRhTzkiGKTsEYViwjdYPOwUWMnxCiGtVsBEYYN6xCcAymcx9d79cr1zpVzHvtu63vTAouuVhMY_TKyWR0sXFpVTw4-dH7mDI6G4JJSX6YS3BmZRvN1cFPwPvj_G32XC5en15m00WpMM-LkmVNGdU1sXhJuSG8xqSyVlvCsISVxsYyTAxGiPG8JVUZXmpNFSeaQ2vxBNzu566D_x5MTKJzUZm2lb3xQxSMY4IIqTLI96AKPsZgrFgH18mwFQiKnXriTz1xVO83xXLr9eGNYdkZfWw8yJXrN4e6jEq2NsheuXjEWNVgmj82AWSPbXybTIhf7bAxQayMbNNK_Hc7_APNloZ6</recordid><startdate>198805</startdate><enddate>198805</enddate><creator>Mikó, Tivadar L</creator><creator>Lampé, László G</creator><creator>Thomázy, Vilmos A</creator><creator>Molnár, Péter</creator><creator>Endes, Pongrác</creator><general>International Society of Gynecological Pathologists</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198805</creationdate><title>Eosinophilic Endomyometritis Associated with Diagnostic Curettage</title><author>Mikó, Tivadar L ; Lampé, László G ; Thomázy, Vilmos A ; Molnár, Péter ; Endes, Pongrác</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3847-4b6575d64f3b58e486342ffdf473a02d3ef734e311781615c75dbdd5c84d80ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Dilatation and Curettage - adverse effects</topic><topic>Endometritis - etiology</topic><topic>Endometritis - pathology</topic><topic>Eosinophilia - etiology</topic><topic>Eosinophilia - pathology</topic><topic>Eosinophils - ultrastructure</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>Mast Cells - ultrastructure</topic><topic>Medical sciences</topic><topic>Microscopy, Electron</topic><topic>Middle Aged</topic><topic>Myometrium - injuries</topic><topic>Non tumoral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mikó, Tivadar L</creatorcontrib><creatorcontrib>Lampé, László G</creatorcontrib><creatorcontrib>Thomázy, Vilmos A</creatorcontrib><creatorcontrib>Molnár, Péter</creatorcontrib><creatorcontrib>Endes, Pongrác</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of gynecological pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mikó, Tivadar L</au><au>Lampé, László G</au><au>Thomázy, Vilmos A</au><au>Molnár, Péter</au><au>Endes, Pongrác</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Eosinophilic Endomyometritis Associated with Diagnostic Curettage</atitle><jtitle>International journal of gynecological pathology</jtitle><addtitle>Int J Gynecol Pathol</addtitle><date>1988-05</date><risdate>1988</risdate><volume>7</volume><issue>2</issue><spage>162</spage><epage>172</epage><pages>162-172</pages><issn>0277-1691</issn><eissn>1538-7151</eissn><coden>IJGPDR</coden><abstract>SUMMARYHistological study of hysterectomy specimens removed for noninflammatory and nonneoplastic disease revealed 15 severe cases and many more slight cases of eosinophil leukocytic endomyometritis, the degree of which appeared to correlate with injury from preoperative diagnostic curettage. In each case of severe eosinophitic endomyometritis, circumferential mucosal and extensive myometrial damage together with an occluding blood clot at the level of the inner orifice was confirmed. The massive eosinophilia appeared any time between 18 h and 21 days after curettage, and it is proposed that the probable causative agents are eosinophil chemotactic substances liberated from the myometrial mast cells and from the degrading blood clot filling the uterine cavity. There were no clinical signs or symptoms that appeared to correlate with the histological changes observed in this study. This phenomenon may serve as a model for studying the dynamics and functions of eosinophilic leukocytes in humans.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>International Society of Gynecological Pathologists</pub><pmid>3397210</pmid><doi>10.1097/00004347-198805000-00007</doi><tpages>11</tpages></addata></record> |
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| ispartof | International journal of gynecological pathology, 1988-05, Vol.7 (2), p.162-172 |
| issn | 0277-1691 1538-7151 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Aged Biological and medical sciences Dilatation and Curettage - adverse effects Endometritis - etiology Endometritis - pathology Eosinophilia - etiology Eosinophilia - pathology Eosinophils - ultrastructure Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Hysterectomy Mast Cells - ultrastructure Medical sciences Microscopy, Electron Middle Aged Myometrium - injuries Non tumoral diseases |
| title | Eosinophilic Endomyometritis Associated with Diagnostic Curettage |
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