Abnormal axonal inward rectification in diabetic neuropathy

An abnormal axonal membrane conductance might contribute to human diabetic neuropathy. To test this idea, we have compared the threshold changes produced by long‐lasting (100–200 ms) de‐ and hyperpolarizing currents applied to median motor and sensory axons at the wrist in 63 diabetic patients with...

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Veröffentlicht in:	Muscle & nerve 1996-10, Vol.19 (10), p.1268-1275
Hauptverfasser:	Horn, Sabine, Quasthoff, Stefan, Grafe, Peter, Bostock, Hugh, Renner, Rolf, Schrank, Berthold
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amyotrophic Lateral Sclerosis - physiopathology Axons - physiology Biological and medical sciences diabetes Diabetic Neuropathies - physiopathology Differential Threshold Electric Conductivity electrophysiology Humans ion channel Ischemia - physiopathology Medical sciences Middle Aged Nervous System - blood supply Nervous system involvement in other diseases. Miscellaneous Neurology pathophysiology peripheral nervous system Reference Values threshold electrotonus
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