A low sperm concentration does not preclude fertility in men with isolated hypogonadotropic hypogonadism after gonadotropin therapy

In order to define the minimal number of sperm needed for conception, we studied semen characteristics of men with isolated hypogonadotropic hypogonadism (IHH) who became sperm-positive during gonadotropin therapy. Twenty-two of 24 men (92%) proved fertile, initiating a total of 40 pregnancies. The...

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Veröffentlicht in:	Fertility and sterility 1988-08, Vol.50 (2), p.343-347
Hauptverfasser:	Burris, Allen S., Clark, Richard V., Vantman, David J., Sherins, Richard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Chorionic Gonadotropin - administration & dosage Drug Therapy, Combination Female Fertility Follicle Stimulating Hormone - blood Gonadotropins, Pituitary - metabolism Gonadotropins, Pituitary - therapeutic use Gynecology. Andrology. Obstetrics Humans Hypogonadism - drug therapy Hypogonadism - metabolism Hypogonadism - pathology Luteinizing Hormone - blood Male Male genital diseases Medical sciences Menotropins - administration & dosage Non tumoral diseases Pregnancy Sperm Count Testis - pathology Testosterone - blood
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Zusammenfassung:	In order to define the minimal number of sperm needed for conception, we studied semen characteristics of men with isolated hypogonadotropic hypogonadism (IHH) who became sperm-positive during gonadotropin therapy. Twenty-two of 24 men (92%) proved fertile, initiating a total of 40 pregnancies. The mean (± standard error of the mean) sperm concentration at the time of conception was 16.7 ± 4.0 × 106/ml. However, 71% of pregnancies were conceived when the mean sperm concentration was
ISSN:	0015-0282 1556-5653
DOI:	10.1016/S0015-0282(16)60084-5