An integrated view of the activities of defibrotide

Defibrotide is a polydeoxyribonucleotide sodium salt extracted from mammalian organs. Its mean molecular weight is 15,000-30,000 daltons. Defibrotide contains aptamers, i.e., single-stranded polynucleotides with a well-defined base sequence and composition (5'-GGTTGG-ATT-GGTTGG-3' and 5�...

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Veröffentlicht in:	Seminars in thrombosis and hemostasis 1996, Vol.22 Suppl 1, p.71-75
Hauptverfasser:	Pescador, R, Porta, R, Ferro, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Fibrinolytic Agents - metabolism Fibrinolytic Agents - pharmacology Fibrinolytic Agents - therapeutic use Humans Inflammation - drug therapy Polydeoxyribonucleotides - metabolism Polydeoxyribonucleotides - pharmacology Polydeoxyribonucleotides - therapeutic use
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