Antidepressants and weight gain

Weight gain is an often reported, but incompletely understood, side effect of many antidepressant medications. We will discuss the literature with respect to the following issues: weight gain as a pharmacological effect of antidepressants or as an effect of recovery from depression; the incidence of...

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Veröffentlicht in:Appetite 1988-04, Vol.10 (2), p.103-117
Hauptverfasser: Russ, Mark J., Ackerman, Sigurd H.
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description Weight gain is an often reported, but incompletely understood, side effect of many antidepressant medications. We will discuss the literature with respect to the following issues: weight gain as a pharmacological effect of antidepressants or as an effect of recovery from depression; the incidence of antidepressant-induced weight gain and possible reasons for individual variability in its occurrence; possible mechanisms of antidepressant-induced weight gain; and options for clinical management. Further elucidation of these issues may contribute to our understanding of the neurobiology of affective disorders and appetitive mechanisms.
doi_str_mv 10.1016/0195-6663(88)90062-1
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subjects antidepressants
Antidepressive Agents - pharmacology
Antidepressive Agents, Tricyclic - pharmacology
Body Weight - drug effects
depression
Eating - drug effects
Feeding Behavior - physiology
Female
Glucose - metabolism
Humans
Insulin - metabolism
Male
Monoamine Oxidase Inhibitors - pharmacology
pharmacology
weight gain
title Antidepressants and weight gain
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