Inhibitors of Glycoprotein Processing Alter T-Cell Proliferative Responses to Antigen and to Interleukin 2

Most of the cell-surface molecules involved in T-cell immune responses are N-linked glycoproteins. We have investigated the effects of inhibitors of glycoprotein processing on specific T-cell functions, with the dual aims of examining the functional role of carbohydrate and of testing the usefulness...

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