Measurement of Ascorbic Acid Kinetics in Man Using Stable Isotopes and Gas Chromatography/Mass Spectrometry

The feasibility of studying ascorbic acid kinetics in man using stable isotope‐labelled tracers and gas chromatographic (GC) separation followed by mass spectrometric (MS) quantitation was assessed. Preliminary studies with 13C‐labelled material showed that although better precision at low levels co...

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Veröffentlicht in:	Journal of mass spectrometry. 1996-07, Vol.31 (7), p.741-748
Hauptverfasser:	Bluck, Leslie J. C., Izzard, Adrian P., Bates, Christopher J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral ascorbic acid Ascorbic Acid - administration & dosage Ascorbic Acid - blood Ascorbic Acid - pharmacokinetics Biological and medical sciences Carbon Isotopes compartmental analysis Gas Chromatography-Mass Spectrometry General pharmacology Humans Linear Models Male Medical sciences Nutritional Physiological Phenomena Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Pilot Projects stable isotopes
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