Agonists of the Ca(2+)-sensing receptor (CaR) activate nonselective cation channels in HEK293 cells stably transfected with the human CaR

Calcium (Ca2+) ions serve multiple roles both intra- and extracellularly. We recently cloned a cell surface, Cao(2+)-sensing receptor (CaR) that plays a central role in Cao2+ homeostasis by enabling direct regulation by Cao2+ of parathyroid hormone (PTH) secretion and the function of other tissues i...

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Veröffentlicht in:	Biochemical and biophysical research communications 1996-09, Vol.226 (2), p.572-579
Hauptverfasser:	Ye, C, Rogers, K, Bai, M, Quinn, S J, Brown, E M, Vassilev, P M
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium-Binding Proteins - drug effects Calcium-Binding Proteins - metabolism Cations Cell Line Humans Ion Channels - drug effects Ion Channels - metabolism Neomycin - pharmacology Receptors, Calcium-Sensing Receptors, Cell Surface - drug effects Receptors, Cell Surface - metabolism Terpenes - pharmacology Thapsigargin Transfection
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