Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging
Quantitative magnetic resonance imaging (MRI) has been used for the in vivo size determination of subcutaneously implanted Dunning R3327–H tumors in male Copenhagen‐Fisher rats (N = 18). Images have been recorded using a multislice spin‐echo sequence SE(1000/36) with a resolution of 0.2 times; 0.2 m...
Gespeichert in:
| Veröffentlicht in: | The Prostate 1988, Vol.12 (4), p.333-341 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 341 |
|---|---|
| container_issue | 4 |
| container_start_page | 333 |
| container_title | The Prostate |
| container_volume | 12 |
| creator | Rudin, M. Qureshi, S. Tolcsvai, L. Siegel, R. A. |
| description | Quantitative magnetic resonance imaging (MRI) has been used for the in vivo size determination of subcutaneously implanted Dunning R3327–H tumors in male Copenhagen‐Fisher rats (N = 18). Images have been recorded using a multislice spin‐echo sequence SE(1000/36) with a resolution of 0.2 times; 0.2 mm2 in the imaging plane and a slice thickness of 2 mm. The reliability in the MRI size determination was of the order of 10%. The MRI results were compared with caliper measurements. Five months after tumor implantation nine rats were castrated. Orchiectomy led to a marked and statistically significant reduction in tumor growth rate as determined by both methods of quantification. Qualitative MRI information regarding the tumor morphology was compared with that for histological specimens. |
| doi_str_mv | 10.1002/pros.2990120407 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78322473</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78322473</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4117-5d7d9e12e7b46a8df01aef3234744bb581ee578489b00078adfd928fe44a1d5f3</originalsourceid><addsrcrecordid>eNqFUMtuFDEQtBAobBLOnJB8QNwm8WtiW5xQFBKkFSEvOFqecTsyzHp2bY8gfD1ezWoRJ04tdVV1VxVCryk5oYSw03Ua8wnTmlBGBJHP0IISLRtCRPscLQiTpBGUy5foMOfvhFQNYQfogHPNhW4XaPM15MkO4bctYYzYRoc3k40l-NDPq9HjkmzM66GuwWE3xRjiI95-LrYALtNqTBmHiJMtGU95i67sY4QSepwgj9HGHnCouwodoxfeDhle7eYRevh4cX9-1SyvLz-df1g2vaBUNq2TTgNlIDtxZpXzhFrwnHEhhei6VlGAViqhdFczSWWdd5opD0JY6lrPj9C7-W41upkgF7MKuYehxoBxykYqzpiQvBJPZ2JfE-UE3qxT9ZqeDCVmW7LZRjV_S66KN7vTU7cCt-fvWq342x1uc28HX-vrQ97TpGopUaTS3s-0n2GAp_99NV9ur-_-MdHM6pAL_NqrbfphziSXrfn2-dLopbi9YeqmWvsDoH2ogw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78322473</pqid></control><display><type>article</type><title>Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Rudin, M. ; Qureshi, S. ; Tolcsvai, L. ; Siegel, R. A.</creator><creatorcontrib>Rudin, M. ; Qureshi, S. ; Tolcsvai, L. ; Siegel, R. A.</creatorcontrib><description>Quantitative magnetic resonance imaging (MRI) has been used for the in vivo size determination of subcutaneously implanted Dunning R3327–H tumors in male Copenhagen‐Fisher rats (N = 18). Images have been recorded using a multislice spin‐echo sequence SE(1000/36) with a resolution of 0.2 times; 0.2 mm2 in the imaging plane and a slice thickness of 2 mm. The reliability in the MRI size determination was of the order of 10%. The MRI results were compared with caliper measurements. Five months after tumor implantation nine rats were castrated. Orchiectomy led to a marked and statistically significant reduction in tumor growth rate as determined by both methods of quantification. Qualitative MRI information regarding the tumor morphology was compared with that for histological specimens.</description><identifier>ISSN: 0270-4137</identifier><identifier>EISSN: 1097-0045</identifier><identifier>DOI: 10.1002/pros.2990120407</identifier><identifier>PMID: 3393495</identifier><identifier>CODEN: PRSTDS</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adenocarcinoma - diagnosis ; Adenocarcinoma - pathology ; Animal tumors. Experimental tumors ; Animals ; Biological and medical sciences ; castration ; Experimental renal and urinary tract tumors ; Magnetic Resonance Imaging - methods ; Male ; Medical sciences ; Neoplasm Transplantation ; nuclear magnetic resonance ; Orchiectomy ; prostate cancer ; Prostatic Neoplasms - diagnosis ; Prostatic Neoplasms - pathology ; Rats ; Rats, Inbred F344 ; Time Factors ; Tumors</subject><ispartof>The Prostate, 1988, Vol.12 (4), p.333-341</ispartof><rights>Copyright © 1988 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4117-5d7d9e12e7b46a8df01aef3234744bb581ee578489b00078adfd928fe44a1d5f3</citedby><cites>FETCH-LOGICAL-c4117-5d7d9e12e7b46a8df01aef3234744bb581ee578489b00078adfd928fe44a1d5f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpros.2990120407$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpros.2990120407$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,4024,27923,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7851080$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3393495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rudin, M.</creatorcontrib><creatorcontrib>Qureshi, S.</creatorcontrib><creatorcontrib>Tolcsvai, L.</creatorcontrib><creatorcontrib>Siegel, R. A.</creatorcontrib><title>Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging</title><title>The Prostate</title><addtitle>Prostate</addtitle><description>Quantitative magnetic resonance imaging (MRI) has been used for the in vivo size determination of subcutaneously implanted Dunning R3327–H tumors in male Copenhagen‐Fisher rats (N = 18). Images have been recorded using a multislice spin‐echo sequence SE(1000/36) with a resolution of 0.2 times; 0.2 mm2 in the imaging plane and a slice thickness of 2 mm. The reliability in the MRI size determination was of the order of 10%. The MRI results were compared with caliper measurements. Five months after tumor implantation nine rats were castrated. Orchiectomy led to a marked and statistically significant reduction in tumor growth rate as determined by both methods of quantification. Qualitative MRI information regarding the tumor morphology was compared with that for histological specimens.</description><subject>Adenocarcinoma - diagnosis</subject><subject>Adenocarcinoma - pathology</subject><subject>Animal tumors. Experimental tumors</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>castration</subject><subject>Experimental renal and urinary tract tumors</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neoplasm Transplantation</subject><subject>nuclear magnetic resonance</subject><subject>Orchiectomy</subject><subject>prostate cancer</subject><subject>Prostatic Neoplasms - diagnosis</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Rats</subject><subject>Rats, Inbred F344</subject><subject>Time Factors</subject><subject>Tumors</subject><issn>0270-4137</issn><issn>1097-0045</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUMtuFDEQtBAobBLOnJB8QNwm8WtiW5xQFBKkFSEvOFqecTsyzHp2bY8gfD1ezWoRJ04tdVV1VxVCryk5oYSw03Ua8wnTmlBGBJHP0IISLRtCRPscLQiTpBGUy5foMOfvhFQNYQfogHPNhW4XaPM15MkO4bctYYzYRoc3k40l-NDPq9HjkmzM66GuwWE3xRjiI95-LrYALtNqTBmHiJMtGU95i67sY4QSepwgj9HGHnCouwodoxfeDhle7eYRevh4cX9-1SyvLz-df1g2vaBUNq2TTgNlIDtxZpXzhFrwnHEhhei6VlGAViqhdFczSWWdd5opD0JY6lrPj9C7-W41upkgF7MKuYehxoBxykYqzpiQvBJPZ2JfE-UE3qxT9ZqeDCVmW7LZRjV_S66KN7vTU7cCt-fvWq342x1uc28HX-vrQ97TpGopUaTS3s-0n2GAp_99NV9ur-_-MdHM6pAL_NqrbfphziSXrfn2-dLopbi9YeqmWvsDoH2ogw</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>Rudin, M.</creator><creator>Qureshi, S.</creator><creator>Tolcsvai, L.</creator><creator>Siegel, R. A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1988</creationdate><title>Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging</title><author>Rudin, M. ; Qureshi, S. ; Tolcsvai, L. ; Siegel, R. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4117-5d7d9e12e7b46a8df01aef3234744bb581ee578489b00078adfd928fe44a1d5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adenocarcinoma - diagnosis</topic><topic>Adenocarcinoma - pathology</topic><topic>Animal tumors. Experimental tumors</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>castration</topic><topic>Experimental renal and urinary tract tumors</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neoplasm Transplantation</topic><topic>nuclear magnetic resonance</topic><topic>Orchiectomy</topic><topic>prostate cancer</topic><topic>Prostatic Neoplasms - diagnosis</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Rats</topic><topic>Rats, Inbred F344</topic><topic>Time Factors</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rudin, M.</creatorcontrib><creatorcontrib>Qureshi, S.</creatorcontrib><creatorcontrib>Tolcsvai, L.</creatorcontrib><creatorcontrib>Siegel, R. A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Prostate</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rudin, M.</au><au>Qureshi, S.</au><au>Tolcsvai, L.</au><au>Siegel, R. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging</atitle><jtitle>The Prostate</jtitle><addtitle>Prostate</addtitle><date>1988</date><risdate>1988</risdate><volume>12</volume><issue>4</issue><spage>333</spage><epage>341</epage><pages>333-341</pages><issn>0270-4137</issn><eissn>1097-0045</eissn><coden>PRSTDS</coden><abstract>Quantitative magnetic resonance imaging (MRI) has been used for the in vivo size determination of subcutaneously implanted Dunning R3327–H tumors in male Copenhagen‐Fisher rats (N = 18). Images have been recorded using a multislice spin‐echo sequence SE(1000/36) with a resolution of 0.2 times; 0.2 mm2 in the imaging plane and a slice thickness of 2 mm. The reliability in the MRI size determination was of the order of 10%. The MRI results were compared with caliper measurements. Five months after tumor implantation nine rats were castrated. Orchiectomy led to a marked and statistically significant reduction in tumor growth rate as determined by both methods of quantification. Qualitative MRI information regarding the tumor morphology was compared with that for histological specimens.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>3393495</pmid><doi>10.1002/pros.2990120407</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0270-4137 |
| ispartof | The Prostate, 1988, Vol.12 (4), p.333-341 |
| issn | 0270-4137 1097-0045 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78322473 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adenocarcinoma - diagnosis Adenocarcinoma - pathology Animal tumors. Experimental tumors Animals Biological and medical sciences castration Experimental renal and urinary tract tumors Magnetic Resonance Imaging - methods Male Medical sciences Neoplasm Transplantation nuclear magnetic resonance Orchiectomy prostate cancer Prostatic Neoplasms - diagnosis Prostatic Neoplasms - pathology Rats Rats, Inbred F344 Time Factors Tumors |
| title | Visualization and quantification of transplanted dunning prostate tumors in rats using magnetic resonance imaging |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T02%3A30%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Visualization%20and%20quantification%20of%20transplanted%20dunning%20prostate%20tumors%20in%20rats%20using%20magnetic%20resonance%20imaging&rft.jtitle=The%20Prostate&rft.au=Rudin,%20M.&rft.date=1988&rft.volume=12&rft.issue=4&rft.spage=333&rft.epage=341&rft.pages=333-341&rft.issn=0270-4137&rft.eissn=1097-0045&rft.coden=PRSTDS&rft_id=info:doi/10.1002/pros.2990120407&rft_dat=%3Cproquest_cross%3E78322473%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78322473&rft_id=info:pmid/3393495&rfr_iscdi=true |