Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage
Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long‐term disability. Obstetricians and neonatologists have recommended deli...
Gespeichert in:
| Veröffentlicht in: | American journal of hematology 1988-06, Vol.28 (2), p.98-102 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 102 |
|---|---|
| container_issue | 2 |
| container_start_page | 98 |
| container_title | American journal of hematology |
| container_volume | 28 |
| creator | Burrows, Robert F. Caco, Chris C. Kelton, John G. |
| description | Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long‐term disability. Obstetricians and neonatologists have recommended delivery by caesarean section and the rapid institution of appropriate treatment for the infant; however, it is theoretically possible that a hemorrhagic event could precede the delivery and consequently not be prevented by these perinatal interventions. In this report we describe a neonate in whom the diagnosis of alloimmune neonatal thrombocytopenia was suspected because of antenatal ultrasound evidence of intracerebral hemorrhage. This case demonstrates the importance of antenatal fetal assessment and indicates the need for the development of therapeutic strategies to maintain fetal hemostasis. |
| doi_str_mv | 10.1002/ajh.2830280207 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78321930</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78321930</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4647-f64085e556f9e0e3418cd1d5528a5104579509c91f14d0de25872f17aa91e50e3</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhoMotVav3oQ9iLfWSTbZTbyVolYpCn6clzQ7a1eym5rsIv33RlrUm6cZmGdmXh5CTilMKAC71O-rCZMpMAkM8j0ypKCyscwE2ydDSDMae1CH5CiEdwBKuYQBGaRMpZzDkDw9oGt1p22irXV10_QtJt3Ku2bpzKZza2xrfZU8r13b6RZdH5K6TfoOvYtN57XxOhI2WWHjvF_pNzwmB5W2AU92dUReb65fZvPx4vH2bjZdjA3PeD6uMg5SoBBZpRAw5VSakpZCMKkFBS5yJUAZRSvKSyiRCZmziuZaK4oiLozIxfbu2ruPHkNXNHUwaO02Z5HLlFGVQgQnW9B4F4LHqlj7utF-U1AoviUWUWLxKzEunO0u98sGyx98Zy3Oz3dzHYy2VVRg6vCD5TlNhWIRU1vss7a4-edpMb2f_4nwBf8Biok</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78321930</pqid></control><display><type>article</type><title>Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Burrows, Robert F. ; Caco, Chris C. ; Kelton, John G.</creator><creatorcontrib>Burrows, Robert F. ; Caco, Chris C. ; Kelton, John G.</creatorcontrib><description>Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long‐term disability. Obstetricians and neonatologists have recommended delivery by caesarean section and the rapid institution of appropriate treatment for the infant; however, it is theoretically possible that a hemorrhagic event could precede the delivery and consequently not be prevented by these perinatal interventions. In this report we describe a neonate in whom the diagnosis of alloimmune neonatal thrombocytopenia was suspected because of antenatal ultrasound evidence of intracerebral hemorrhage. This case demonstrates the importance of antenatal fetal assessment and indicates the need for the development of therapeutic strategies to maintain fetal hemostasis.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.2830280207</identifier><identifier>PMID: 3293440</identifier><identifier>CODEN: AJHEDD</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Biological and medical sciences ; Brain Diseases - complications ; Brain Diseases - diagnostic imaging ; Cerebral Hemorrhage - diagnosis ; Cerebral Hemorrhage - etiology ; Cysts - complications ; Cysts - diagnostic imaging ; Female ; Fetal Diseases - diagnosis ; Fetal Diseases - etiology ; fetal intracranial hemorrhage ; Hematologic and hematopoietic diseases ; Humans ; Immune System Diseases - complications ; Immune System Diseases - diagnosis ; Immune System Diseases - immunology ; Infant, Newborn ; Isoantibodies - analysis ; Medical sciences ; Platelet diseases and coagulopathies ; porencephalic cysts ; Pregnancy ; Prenatal Diagnosis ; Thrombocytopenia - complications ; Thrombocytopenia - diagnosis ; Thrombocytopenia - immunology ; Tomography, X-Ray Computed ; Ultrasonography</subject><ispartof>American journal of hematology, 1988-06, Vol.28 (2), p.98-102</ispartof><rights>Copyright © 1988 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4647-f64085e556f9e0e3418cd1d5528a5104579509c91f14d0de25872f17aa91e50e3</citedby><cites>FETCH-LOGICAL-c4647-f64085e556f9e0e3418cd1d5528a5104579509c91f14d0de25872f17aa91e50e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.2830280207$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.2830280207$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7713592$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3293440$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burrows, Robert F.</creatorcontrib><creatorcontrib>Caco, Chris C.</creatorcontrib><creatorcontrib>Kelton, John G.</creatorcontrib><title>Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long‐term disability. Obstetricians and neonatologists have recommended delivery by caesarean section and the rapid institution of appropriate treatment for the infant; however, it is theoretically possible that a hemorrhagic event could precede the delivery and consequently not be prevented by these perinatal interventions. In this report we describe a neonate in whom the diagnosis of alloimmune neonatal thrombocytopenia was suspected because of antenatal ultrasound evidence of intracerebral hemorrhage. This case demonstrates the importance of antenatal fetal assessment and indicates the need for the development of therapeutic strategies to maintain fetal hemostasis.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Brain Diseases - complications</subject><subject>Brain Diseases - diagnostic imaging</subject><subject>Cerebral Hemorrhage - diagnosis</subject><subject>Cerebral Hemorrhage - etiology</subject><subject>Cysts - complications</subject><subject>Cysts - diagnostic imaging</subject><subject>Female</subject><subject>Fetal Diseases - diagnosis</subject><subject>Fetal Diseases - etiology</subject><subject>fetal intracranial hemorrhage</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Immune System Diseases - complications</subject><subject>Immune System Diseases - diagnosis</subject><subject>Immune System Diseases - immunology</subject><subject>Infant, Newborn</subject><subject>Isoantibodies - analysis</subject><subject>Medical sciences</subject><subject>Platelet diseases and coagulopathies</subject><subject>porencephalic cysts</subject><subject>Pregnancy</subject><subject>Prenatal Diagnosis</subject><subject>Thrombocytopenia - complications</subject><subject>Thrombocytopenia - diagnosis</subject><subject>Thrombocytopenia - immunology</subject><subject>Tomography, X-Ray Computed</subject><subject>Ultrasonography</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVav3oQ9iLfWSTbZTbyVolYpCn6clzQ7a1eym5rsIv33RlrUm6cZmGdmXh5CTilMKAC71O-rCZMpMAkM8j0ypKCyscwE2ydDSDMae1CH5CiEdwBKuYQBGaRMpZzDkDw9oGt1p22irXV10_QtJt3Ku2bpzKZza2xrfZU8r13b6RZdH5K6TfoOvYtN57XxOhI2WWHjvF_pNzwmB5W2AU92dUReb65fZvPx4vH2bjZdjA3PeD6uMg5SoBBZpRAw5VSakpZCMKkFBS5yJUAZRSvKSyiRCZmziuZaK4oiLozIxfbu2ruPHkNXNHUwaO02Z5HLlFGVQgQnW9B4F4LHqlj7utF-U1AoviUWUWLxKzEunO0u98sGyx98Zy3Oz3dzHYy2VVRg6vCD5TlNhWIRU1vss7a4-edpMb2f_4nwBf8Biok</recordid><startdate>198806</startdate><enddate>198806</enddate><creator>Burrows, Robert F.</creator><creator>Caco, Chris C.</creator><creator>Kelton, John G.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198806</creationdate><title>Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage</title><author>Burrows, Robert F. ; Caco, Chris C. ; Kelton, John G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4647-f64085e556f9e0e3418cd1d5528a5104579509c91f14d0de25872f17aa91e50e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Brain Diseases - complications</topic><topic>Brain Diseases - diagnostic imaging</topic><topic>Cerebral Hemorrhage - diagnosis</topic><topic>Cerebral Hemorrhage - etiology</topic><topic>Cysts - complications</topic><topic>Cysts - diagnostic imaging</topic><topic>Female</topic><topic>Fetal Diseases - diagnosis</topic><topic>Fetal Diseases - etiology</topic><topic>fetal intracranial hemorrhage</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Immune System Diseases - complications</topic><topic>Immune System Diseases - diagnosis</topic><topic>Immune System Diseases - immunology</topic><topic>Infant, Newborn</topic><topic>Isoantibodies - analysis</topic><topic>Medical sciences</topic><topic>Platelet diseases and coagulopathies</topic><topic>porencephalic cysts</topic><topic>Pregnancy</topic><topic>Prenatal Diagnosis</topic><topic>Thrombocytopenia - complications</topic><topic>Thrombocytopenia - diagnosis</topic><topic>Thrombocytopenia - immunology</topic><topic>Tomography, X-Ray Computed</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burrows, Robert F.</creatorcontrib><creatorcontrib>Caco, Chris C.</creatorcontrib><creatorcontrib>Kelton, John G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burrows, Robert F.</au><au>Caco, Chris C.</au><au>Kelton, John G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>1988-06</date><risdate>1988</risdate><volume>28</volume><issue>2</issue><spage>98</spage><epage>102</epage><pages>98-102</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><coden>AJHEDD</coden><abstract>Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long‐term disability. Obstetricians and neonatologists have recommended delivery by caesarean section and the rapid institution of appropriate treatment for the infant; however, it is theoretically possible that a hemorrhagic event could precede the delivery and consequently not be prevented by these perinatal interventions. In this report we describe a neonate in whom the diagnosis of alloimmune neonatal thrombocytopenia was suspected because of antenatal ultrasound evidence of intracerebral hemorrhage. This case demonstrates the importance of antenatal fetal assessment and indicates the need for the development of therapeutic strategies to maintain fetal hemostasis.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>3293440</pmid><doi>10.1002/ajh.2830280207</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0361-8609 |
| ispartof | American journal of hematology, 1988-06, Vol.28 (2), p.98-102 |
| issn | 0361-8609 1096-8652 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78321930 |
| source | MEDLINE; Wiley Journals |
| subjects | Adult Biological and medical sciences Brain Diseases - complications Brain Diseases - diagnostic imaging Cerebral Hemorrhage - diagnosis Cerebral Hemorrhage - etiology Cysts - complications Cysts - diagnostic imaging Female Fetal Diseases - diagnosis Fetal Diseases - etiology fetal intracranial hemorrhage Hematologic and hematopoietic diseases Humans Immune System Diseases - complications Immune System Diseases - diagnosis Immune System Diseases - immunology Infant, Newborn Isoantibodies - analysis Medical sciences Platelet diseases and coagulopathies porencephalic cysts Pregnancy Prenatal Diagnosis Thrombocytopenia - complications Thrombocytopenia - diagnosis Thrombocytopenia - immunology Tomography, X-Ray Computed Ultrasonography |
| title | Neonatal alloimmune thrombocytopenia: Spontaneous in utero intracranial hemorrhage |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T16%3A18%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Neonatal%20alloimmune%20thrombocytopenia:%20Spontaneous%20in%20utero%20intracranial%20hemorrhage&rft.jtitle=American%20journal%20of%20hematology&rft.au=Burrows,%20Robert%20F.&rft.date=1988-06&rft.volume=28&rft.issue=2&rft.spage=98&rft.epage=102&rft.pages=98-102&rft.issn=0361-8609&rft.eissn=1096-8652&rft.coden=AJHEDD&rft_id=info:doi/10.1002/ajh.2830280207&rft_dat=%3Cproquest_cross%3E78321930%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78321930&rft_id=info:pmid/3293440&rfr_iscdi=true |