Rev/RRE-Independent Mason–Pfizer Monkey Virus Constitutive Transport Element-Dependent Propagation of SIVmac239 Vectors Using a Single Round of Replication Assay

In a step toward creating live-attenuated or DNA subunit vaccines for AIDS, the replication of simian immunodeficiency virus (SIV) was studied independently of the Rev and RRE (Rev-responsive element) regulatory system, over a single round. To accomplish this, theenvgene of an SIV vector was made de...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1996-08, Vol.222 (2), p.457-463
Hauptverfasser:	Rizvi, Tahir A., Schmidt, Russell D., Lew, Kathy A., Keeling, Michale E.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Cell Line, Transformed Cercopithecus aethiops Gene Products, rev - genetics Gene Products, rev - physiology Genes, env Genetic Vectors HeLa Cells HIV-1 - genetics HIV-1 - physiology Humans Mason-Pfizer monkey virus - genetics Regulatory Sequences, Nucleic Acid rev Gene Products, Human Immunodeficiency Virus simian immunodeficiency virus Simian Immunodeficiency Virus - genetics Simian Immunodeficiency Virus - physiology Virus Replication - genetics
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