Regulation of inducible nitric oxide synthase expression in IFN-gamma- treated murine macrophages cultured under hypoxic conditions

We recently reported that a hypoxia-responsive element mediates a novel pathway of transcriptional activation of the inducible nitric oxide synthase (iNOS) promoter in murine macrophages treated with IFN-gamma plus hypoxia (1% O2). In this study, we investigated the expression of NOS activity and th...

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