Demonstration of the Potent Antihypertensive Activity of Phenyl-2-Aminoethyl Sulfides

In previous work we established that phenyl-2-aminoethyl sulfide (PAES) and derivatives of this basic structure are novel substrate analogs for the adrenergic synthetic enzyme, dopamine β-monooxygenase (DBM). We examined the in vivo effects of infusions of PAES and ring-hydroxylated (HOPAES) and/or...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1988-05, Vol.11 (5), p.501-510
Hauptverfasser:	Herman, Heath H, Pollock, Stanley H, Fowler, Lydia C, May, Sheldon W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Animals Antihypertensive agents Antihypertensive Agents - pharmacology Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Cocaine - pharmacology Dogs Drug Tolerance Ethylamines - pharmacology Male Medical sciences Pharmacology. Drug treatments Rats Rats, Inbred SHR Sympathomimetics Time Factors
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