Crystal structure of UDP- N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin

Background The ever increasing number of antibiotic resistant bacteria has fuelled interest in the development of new antibiotics and other antibacterial agents. The major structural element of the bacterial cell wall is the heteropolymer peptidoglycan and the enzymes of peptidoglycan biosynthesis a...

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